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From the Clinic to the Bench and Back Again in One Dog Year: How a Cross-Species Pipeline to Identify New Treatments for Sarcoma Illuminates the Path Forward in Precision Medicine.
Rao SR, Somarelli JA, Altunel E, Selmic LE, Byrum M, Sheth MU, Cheng S, Ware KE, Kim SY, Prinz JA, Devos N, Corcoran DL, Moseley A, Soderblom E, Hsu SD, Eward WC. Rao SR, et al. Among authors: kim sy. Front Oncol. 2020 Feb 11;10:117. doi: 10.3389/fonc.2020.00117. eCollection 2020. Front Oncol. 2020. PMID: 32117764 Free PMC article.
A Precision Medicine Drug Discovery Pipeline Identifies Combined CDK2 and 9 Inhibition as a Novel Therapeutic Strategy in Colorectal Cancer.
Somarelli JA, Roghani RS, Moghaddam AS, Thomas BC, Rupprecht G, Ware KE, Altunel E, Mantyh JB, Kim SY, McCall SJ, Shen X, Mantyh CR, Hsu DS. Somarelli JA, et al. Among authors: kim sy. Mol Cancer Ther. 2020 Dec;19(12):2516-2527. doi: 10.1158/1535-7163.MCT-20-0454. Epub 2020 Nov 6. Mol Cancer Ther. 2020. PMID: 33158998 Free PMC article.
A Comparative Oncology Drug Discovery Pipeline to Identify and Validate New Treatments for Osteosarcoma.
Somarelli JA, Rupprecht G, Altunel E, Flamant EM, Rao S, Sivaraj D, Lazarides AL, Hoskinson SM, Sheth MU, Cheng S, Kim SY, Ware KE, Agarwal A, Cullen MM, Selmic LE, Everitt JI, McCall SJ, Eward C, Eward WC, Hsu DS. Somarelli JA, et al. Among authors: kim sy. Cancers (Basel). 2020 Nov 11;12(11):3335. doi: 10.3390/cancers12113335. Cancers (Basel). 2020. PMID: 33187254 Free PMC article.
A synthetic lethal screen for Snail-induced enzalutamide resistance identifies JAK/STAT signaling as a therapeutic vulnerability in prostate cancer.
Ware KE, Thomas BC, Olawuni PD, Sheth MU, Hawkey N, Yeshwanth M, Miller BC, Vietor KJ, Jolly MK, Kim SY, Armstrong AJ, Somarelli JA. Ware KE, et al. Among authors: kim sy. Front Mol Biosci. 2023 May 9;10:1104505. doi: 10.3389/fmolb.2023.1104505. eCollection 2023. Front Mol Biosci. 2023. PMID: 37228586 Free PMC article.
Identification of Novel Mast Cell Activators Using Cell-Based High-Throughput Screening.
Choi HW, Chan C, Shterev ID, Lynch HE, Robinette TJ, Johnson-Weaver BT, Shi J, Sempowski GD, Kim SY, Dickson JK, Gooden DM, Abraham SN, Staats HF. Choi HW, et al. Among authors: kim sy. SLAS Discov. 2019 Jul;24(6):628-640. doi: 10.1177/2472555219834699. Epub 2019 Mar 27. SLAS Discov. 2019. PMID: 30917061 Free PMC article.
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