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Page 1
Manno-epi-cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors.
Armstrong Z, Kuo CL, Lahav D, Liu B, Johnson R, Beenakker TJM, de Boer C, Wong CS, van Rijssel ER, Debets MF, Florea BI, Hissink C, Boot RG, Geurink PP, Ovaa H, van der Stelt M, van der Marel GM, Codée JDC, Aerts JMFG, Wu L, Overkleeft HS, Davies GJ. Armstrong Z, et al. Among authors: beenakker tjm. J Am Chem Soc. 2020 Jul 29;142(30):13021-13029. doi: 10.1021/jacs.0c03880. Epub 2020 Jul 16. J Am Chem Soc. 2020. PMID: 32605368
Fluorous linker facilitated synthesis of teichoic acid fragments.
Hogendorf WF, Lameijer LN, Beenakker TJ, Overkleeft HS, Filippov DV, Codée JD, Van der Marel GA. Hogendorf WF, et al. Org Lett. 2012 Feb 3;14(3):848-51. doi: 10.1021/ol2033652. Epub 2012 Jan 20. Org Lett. 2012. PMID: 22264133
Potent and selective activity-based probes for GH27 human retaining α-galactosidases.
Willems LI, Beenakker TJ, Murray B, Scheij S, Kallemeijn WW, Boot RG, Verhoek M, Donker-Koopman WE, Ferraz MJ, van Rijssel ER, Florea BI, Codée JD, van der Marel GA, Aerts JM, Overkleeft HS. Willems LI, et al. J Am Chem Soc. 2014 Aug 20;136(33):11622-5. doi: 10.1021/ja507040n. Epub 2014 Aug 11. J Am Chem Soc. 2014. PMID: 25105979
Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors.
Beenakker TJM, Wander DPA, Offen WA, Artola M, Raich L, Ferraz MJ, Li KY, Houben JHPM, van Rijssel ER, Hansen T, van der Marel GA, Codée JDC, Aerts JMFG, Rovira C, Davies GJ, Overkleeft HS. Beenakker TJM, et al. J Am Chem Soc. 2017 May 17;139(19):6534-6537. doi: 10.1021/jacs.7b01773. Epub 2017 May 5. J Am Chem Soc. 2017. PMID: 28463498 Free PMC article.
Human Alpha Galactosidases Transiently Produced in Nicotiana benthamiana Leaves: New Insights in Substrate Specificities with Relevance for Fabry Disease.
Kytidou K, Beenakker TJM, Westerhof LB, Hokke CH, Moolenaar GF, Goosen N, Mirzaian M, Ferraz MJ, de Geus M, Kallemeijn WW, Overkleeft HS, Boot RG, Schots A, Bosch D, Aerts JMFG. Kytidou K, et al. Among authors: beenakker tjm. Front Plant Sci. 2017 Jun 21;8:1026. doi: 10.3389/fpls.2017.01026. eCollection 2017. Front Plant Sci. 2017. PMID: 28680430 Free PMC article.
Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines.
Schröder SP, van de Sande JW, Kallemeijn WW, Kuo CL, Artola M, van Rooden EJ, Jiang J, Beenakker TJM, Florea BI, Offen WA, Davies GJ, Minnaard AJ, Aerts JMFG, Codée JDC, van der Marel GA, Overkleeft HS. Schröder SP, et al. Among authors: beenakker tjm. Chem Commun (Camb). 2017 Nov 21;53(93):12528-12531. doi: 10.1039/c7cc07730k. Chem Commun (Camb). 2017. PMID: 29116266
Spiro-epoxyglycosides as Activity-Based Probes for Glycoside Hydrolase Family 99 Endomannosidase/Endomannanase.
Schröder SP, Kallemeijn WW, Debets MF, Hansen T, Sobala LF, Hakki Z, Williams SJ, Beenakker TJM, Aerts JMFG, van der Marel GA, Codée JDC, Davies GJ, Overkleeft HS. Schröder SP, et al. Among authors: beenakker tjm. Chemistry. 2018 Jul 11;24(39):9983-9992. doi: 10.1002/chem.201801902. Epub 2018 Jun 21. Chemistry. 2018. PMID: 29797675 Free PMC article.
Synthesis of broad-specificity activity-based probes for exo-β-mannosidases.
McGregor NGS, Kuo CL, Beenakker TJM, Wong CS, Offen WA, Armstrong Z, Florea BI, Codée JDC, Overkleeft HS, Aerts JMFG, Davies GJ. McGregor NGS, et al. Among authors: beenakker tjm. Org Biomol Chem. 2022 Jan 26;20(4):877-886. doi: 10.1039/d1ob02287c. Org Biomol Chem. 2022. PMID: 35015006 Free PMC article.
The development of a broad-spectrum retaining β-exo-galactosidase activity-based probe.
Kuo CL, Su Q, van den Nieuwendijk AMCH, Beenakker TJM, Offen WA, Willems LI, Boot RG, Sarris AJ, Marques ARA, Codée JDC, van der Marel GA, Florea BI, Davies GJ, Overkleeft HS, Aerts JMFG. Kuo CL, et al. Among authors: beenakker tjm. Org Biomol Chem. 2023 Oct 4;21(38):7813-7820. doi: 10.1039/d3ob01261a. Org Biomol Chem. 2023. PMID: 37724332
12 results