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Early single-dose exosome treatment improves neurologic outcomes in a 7-day swine model of traumatic brain injury and hemorrhagic shock.
Williams AM, Wu Z, Bhatti UF, Biesterveld BE, Kemp MT, Wakam GK, Vercruysse CA, Chtraklin K, Siddiqui AZ, Pickell Z, Dekker SE, Tian Y, Liu B, Li Y, Buller B, Alam HB. Williams AM, et al. Among authors: wakam gk. J Trauma Acute Care Surg. 2020 Aug;89(2):388-396. doi: 10.1097/TA.0000000000002698. J Trauma Acute Care Surg. 2020. PMID: 32218019
Early treatment with exosomes following traumatic brain injury and hemorrhagic shock in a swine model promotes transcriptional changes associated with neuroprotection.
Williams AM, Higgins GA, Bhatti UF, Biesterveld BE, Dekker SE, Kathawate RG, Tian Y, Wu Z, Kemp MT, Wakam GK, Liu B, Li Y, Buller B, Alam HB. Williams AM, et al. Among authors: wakam gk. J Trauma Acute Care Surg. 2020 Sep;89(3):536-543. doi: 10.1097/TA.0000000000002815. J Trauma Acute Care Surg. 2020. PMID: 32658440
Valproic acid treatment rescues injured tissues after traumatic brain injury.
Biesterveld BE, Pumiglia L, Iancu A, Shamshad AA, Remmer HA, Siddiqui AZ, O'Connell RL, Wakam GK, Kemp MT, Williams AM, Pai MP, Alam HB. Biesterveld BE, et al. Among authors: wakam gk. J Trauma Acute Care Surg. 2020 Dec;89(6):1156-1165. doi: 10.1097/TA.0000000000002918. J Trauma Acute Care Surg. 2020. PMID: 32890344 Free PMC article.
Administration of valproic acid in clinically approved dose improves neurologic recovery and decreases brain lesion size in swine subjected to hemorrhagic shock and traumatic brain injury.
Wakam GK, Biesterveld BE, Pai MP, Kemp MT, O'Connell RL, Williams AM, Srinivasan A, Chtraklin K, Siddiqui AZ, Bhatti UF, Vercruysse CA, Alam HB. Wakam GK, et al. J Trauma Acute Care Surg. 2021 Feb 1;90(2):346-352. doi: 10.1097/TA.0000000000003036. J Trauma Acute Care Surg. 2021. PMID: 33230090
43 results