Mottram JC - Search Results

1

Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors.

Saldivia M, Fang E, Ma X, Myburgh E, Carnielli JBT, Bower-Lepts C, Brown E, Ritchie R, Lakshminarayana SB, Chen YL, Patra D, Ornelas E, Koh HXY, Williams SL, Supek F, Paape D, McCulloch R, Kaiser M, Barrett MP, Jiricek J, Diagana TT, Mottram JC, Rao SPS. Saldivia M, et al. Among authors: mottram jc. Nat Microbiol. 2020 Oct;5(10):1207-1216. doi: 10.1038/s41564-020-0745-6. Epub 2020 Jul 13. Nat Microbiol. 2020. PMID: 32661312 Free PMC article.

2

Recent advances in identifying and validating drug targets in trypanosomes and leishmanias.

Barrett MP, Mottram JC, Coombs GH. Barrett MP, et al. Among authors: mottram jc. Trends Microbiol. 1999 Feb;7(2):82-8. doi: 10.1016/s0966-842x(98)01433-4. Trends Microbiol. 1999. PMID: 10081086 Review.

3

Stable transformation of trypanosomatids through targeted chromosomal integration of the selectable marker gene encoding blasticidin S deaminase.

Brooks DR, McCulloch R, Coombs GH, Mottram JC. Brooks DR, et al. Among authors: mottram jc. FEMS Microbiol Lett. 2000 May 15;186(2):287-91. doi: 10.1111/j.1574-6968.2000.tb09119.x. FEMS Microbiol Lett. 2000. PMID: 10802186

4

Trypanosoma brucei Polo-like kinase is essential for basal body duplication, kDNA segregation and cytokinesis.

Hammarton TC, Kramer S, Tetley L, Boshart M, Mottram JC. Hammarton TC, et al. Among authors: mottram jc. Mol Microbiol. 2007 Sep;65(5):1229-48. doi: 10.1111/j.1365-2958.2007.05866.x. Epub 2007 Jul 27. Mol Microbiol. 2007. PMID: 17662039 Free PMC article.

5

Searching for novel cell cycle regulators in Trypanosoma brucei with an RNA interference screen.

Monnerat S, Clucas C, Brown E, Mottram JC, Hammarton TC. Monnerat S, et al. Among authors: mottram jc. BMC Res Notes. 2009 Mar 23;2:46. doi: 10.1186/1756-0500-2-46. BMC Res Notes. 2009. PMID: 19309510 Free PMC article.

6

Recombinant Leishmania mexicana CRK3:CYCA has protein kinase activity in the absence of phosphorylation on the T-loop residue Thr178.

Gomes FC, Ali NO, Brown E, Walker RG, Grant KM, Mottram JC. Gomes FC, et al. Among authors: mottram jc. Mol Biochem Parasitol. 2010 Jun;171(2):89-96. doi: 10.1016/j.molbiopara.2010.03.002. Epub 2010 Mar 23. Mol Biochem Parasitol. 2010. PMID: 20338198 Free PMC article.

7

Imaging of the host/parasite interplay in cutaneous leishmaniasis.

Millington OR, Myburgh E, Mottram JC, Alexander J. Millington OR, et al. Among authors: mottram jc. Exp Parasitol. 2010 Nov;126(3):310-7. doi: 10.1016/j.exppara.2010.05.014. Epub 2010 May 23. Exp Parasitol. 2010. PMID: 20501336 Free PMC article. Review.

8

Oligopeptidase B deficient mutants of Leishmania major.

Munday JC, McLuskey K, Brown E, Coombs GH, Mottram JC. Munday JC, et al. Among authors: mottram jc. Mol Biochem Parasitol. 2011 Jan;175(1):49-57. doi: 10.1016/j.molbiopara.2010.09.003. Epub 2010 Sep 29. Mol Biochem Parasitol. 2011. PMID: 20883728 Free PMC article.

9

High throughput screens yield small molecule inhibitors of Leishmania CRK3:CYC6 cyclin-dependent kinase.

Walker RG, Thomson G, Malone K, Nowicki MW, Brown E, Blake DG, Turner NJ, Walkinshaw MD, Grant KM, Mottram JC. Walker RG, et al. Among authors: mottram jc. PLoS Negl Trop Dis. 2011 Apr 5;5(4):e1033. doi: 10.1371/journal.pntd.0001033. PLoS Negl Trop Dis. 2011. PMID: 21483720 Free PMC article.

10

Leishmania mexicana metacaspase is a negative regulator of amastigote proliferation in mammalian cells.

Castanys-Muñoz E, Brown E, Coombs GH, Mottram JC. Castanys-Muñoz E, et al. Among authors: mottram jc. Cell Death Dis. 2012 Sep 6;3(9):e385. doi: 10.1038/cddis.2012.113. Cell Death Dis. 2012. PMID: 22951982 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

261 results

Search Page

Filters