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Structure-based development of a subtype-selective orexin 1 receptor antagonist.
Hellmann J, Drabek M, Yin J, Gunera J, Pröll T, Kraus F, Langmead CJ, Hübner H, Weikert D, Kolb P, Rosenbaum DM, Gmeiner P. Hellmann J, et al. Among authors: kolb p. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):18059-18067. doi: 10.1073/pnas.2002704117. Epub 2020 Jul 15. Proc Natl Acad Sci U S A. 2020. PMID: 32669442 Free PMC article.
Structure-based discovery of beta2-adrenergic receptor ligands.
Kolb P, Rosenbaum DM, Irwin JJ, Fung JJ, Kobilka BK, Shoichet BK. Kolb P, et al. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6843-8. doi: 10.1073/pnas.0812657106. Epub 2009 Apr 2. Proc Natl Acad Sci U S A. 2009. PMID: 19342484 Free PMC article.
GPCRdb: the G protein-coupled receptor database - an introduction.
Munk C, Isberg V, Mordalski S, Harpsøe K, Rataj K, Hauser AS, Kolb P, Bojarski AJ, Vriend G, Gloriam DE. Munk C, et al. Among authors: kolb p. Br J Pharmacol. 2016 Jul;173(14):2195-207. doi: 10.1111/bph.13509. Epub 2016 Jun 3. Br J Pharmacol. 2016. PMID: 27155948 Free PMC article. Review.
Interrogating dense ligand chemical space with a forward-synthetic library.
Chevillard F, Stotani S, Karawajczyk A, Hristeva S, Pardon E, Steyaert J, Tzalis D, Kolb P. Chevillard F, et al. Among authors: kolb p. Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11496-11501. doi: 10.1073/pnas.1818718116. Epub 2019 May 21. Proc Natl Acad Sci U S A. 2019. PMID: 31113876 Free PMC article.
191 results