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Expression-Driven Genetic Dependency Reveals Targets for Precision Medicine.
Elmas A, Layden HM, Ellis JD, Bartlett LN, Zhao X, Kawabata-Iwakawa R, Obinata H, Hiebert SW, Huang KL. Elmas A, et al. Among authors: huang kl. bioRxiv [Preprint]. 2024 Oct 21:2024.10.17.618926. doi: 10.1101/2024.10.17.618926. bioRxiv. 2024. PMID: 39484404 Free PMC article. Preprint.
Deletions Rate-Limit Breast and Ovarian Cancer Initiation.
Houlahan KE, Bihie M, Contreras JG, Fulop DJ, Lopez G, Huang HH, Van Loo P, Curtis C, Boutros PC, Huang KL. Houlahan KE, et al. Among authors: huang kl. bioRxiv [Preprint]. 2024 Oct 21:2024.10.17.618945. doi: 10.1101/2024.10.17.618945. bioRxiv. 2024. PMID: 39484366 Free PMC article. Preprint.
A community effort to optimize sequence-based deep learning models of gene regulation.
Rafi AM, Nogina D, Penzar D, Lee D, Lee D, Kim N, Kim S, Kim D, Shin Y, Kwak IY, Meshcheryakov G, Lando A, Zinkevich A, Kim BC, Lee J, Kang T, Vaishnav ED, Yadollahpour P; Random Promoter DREAM Challenge Consortium; Kim S, Albrecht J, Regev A, Gong W, Kulakovskiy IV, Meyer P, de Boer CG. Rafi AM, et al. Nat Biotechnol. 2024 Oct 11. doi: 10.1038/s41587-024-02414-w. Online ahead of print. Nat Biotechnol. 2024. PMID: 39394483
The TRIM-NHL RNA-binding protein Brain Tumor coordinately regulates expression of the glycolytic pathway and vacuolar ATPase complex.
Connacher RP, Roden RT, Huang KL, Korte AJ, Yeruva S, Dittbenner N, DesMarais AJ, Weidmann CA, Randall TA, Williams J, Hall TMT, Wagner EJ, Goldstrohm AC. Connacher RP, et al. Among authors: huang kl. Nucleic Acids Res. 2024 Nov 11;52(20):12669-12688. doi: 10.1093/nar/gkae810. Nucleic Acids Res. 2024. PMID: 39351871 Free PMC article.
681 results