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Topoisomerase III-β is required for efficient replication of positive-sense RNA viruses.
Prasanth KR, Hirano M, Fagg WS, McAnarney ET, Shan C, Xie X, Hage A, Pietzsch CA, Bukreyev A, Rajsbaum R, Shi PY, Bedford MT, Bradrick SS, Menachery V, Garcia-Blanco MA. Prasanth KR, et al. Among authors: bedford mt. Antiviral Res. 2020 Oct;182:104874. doi: 10.1016/j.antiviral.2020.104874. Epub 2020 Jul 28. Antiviral Res. 2020. PMID: 32735900 Free PMC article.
Topoisomerase III-ß is required for efficient replication of positive-sense RNA viruses.
Prasanth KR, Hirano M, Fagg WS, McAnarney ET, Shan C, Xie X, Hage A, Pietzsch CA, Bukreyev A, Rajsbaum R, Shi PY, Bedford MT, Bradrick SS, Menachery V, Garcia-Blanco MA. Prasanth KR, et al. Among authors: bedford mt. bioRxiv [Preprint]. 2020 Mar 27:2020.03.24.005900. doi: 10.1101/2020.03.24.005900. bioRxiv. 2020. Update in: Antiviral Res. 2020 Oct;182:104874. doi: 10.1016/j.antiviral.2020.104874. PMID: 32511318 Free PMC article. Updated. Preprint.
Ubiquitin Ligase WWP1 Interacts with Ebola Virus VP40 To Regulate Egress.
Han Z, Sagum CA, Takizawa F, Ruthel G, Berry CT, Kong J, Sunyer JO, Freedman BD, Bedford MT, Sidhu SS, Sudol M, Harty RN. Han Z, et al. Among authors: bedford mt. J Virol. 2017 Sep 27;91(20):e00812-17. doi: 10.1128/JVI.00812-17. Print 2017 Oct 15. J Virol. 2017. PMID: 28768865 Free PMC article.
CARM1 regulates replication fork speed and stress response by stimulating PARP1.
Genois MM, Gagné JP, Yasuhara T, Jackson J, Saxena S, Langelier MF, Ahel I, Bedford MT, Pascal JM, Vindigni A, Poirier GG, Zou L. Genois MM, et al. Among authors: bedford mt. Mol Cell. 2021 Feb 18;81(4):784-800.e8. doi: 10.1016/j.molcel.2020.12.010. Epub 2021 Jan 6. Mol Cell. 2021. PMID: 33412112 Free PMC article.
Enzymatic activity is required for the in vivo functions of CARM1.
Kim D, Lee J, Cheng D, Li J, Carter C, Richie E, Bedford MT. Kim D, et al. Among authors: bedford mt. J Biol Chem. 2010 Jan 8;285(2):1147-52. doi: 10.1074/jbc.M109.035865. Epub 2009 Nov 5. J Biol Chem. 2010. PMID: 19897492 Free PMC article.
PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition.
Li Y, Dobrolecki LE, Sallas C, Zhang X, Kerr TD, Bisht D, Wang Y, Awasthi S, Kaundal B, Wu S, Peng W, Mendillo ML, Lu Y, Jeter CR, Peng G, Liu J, Westin SN, Sood AK, Lewis MT, Das J, Yi SS, Bedford MT, McGrail DJ, Sahni N. Li Y, et al. Among authors: bedford mt. Cell Rep Med. 2023 Dec 19;4(12):101326. doi: 10.1016/j.xcrm.2023.101326. Cell Rep Med. 2023. PMID: 38118413 Free PMC article.
226 results