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beta-Amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or beta-amyloid deposits.
Malm T, Ort M, Tähtivaara L, Jukarainen N, Goldsteins G, Puoliväli J, Nurmi A, Pussinen R, Ahtoniemi T, Miettinen TK, Kanninen K, Leskinen S, Vartiainen N, Yrjänheikki J, Laatikainen R, Harris-White ME, Koistinaho M, Frautschy SA, Bures J, Koistinaho J. Malm T, et al. Proc Natl Acad Sci U S A. 2006 Jun 6;103(23):8852-7. doi: 10.1073/pnas.0602896103. Epub 2006 May 24. Proc Natl Acad Sci U S A. 2006. PMID: 16723396 Free PMC article.
Nuclear factor erythroid 2-related factor 2 protects against beta amyloid.
Kanninen K, Malm TM, Jyrkkänen HK, Goldsteins G, Keksa-Goldsteine V, Tanila H, Yamamoto M, Ylä-Herttuala S, Levonen AL, Koistinaho J. Kanninen K, et al. Mol Cell Neurosci. 2008 Nov;39(3):302-13. doi: 10.1016/j.mcn.2008.07.010. Epub 2008 Jul 29. Mol Cell Neurosci. 2008. PMID: 18706502
Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease.
Kanninen K, Heikkinen R, Malm T, Rolova T, Kuhmonen S, Leinonen H, Ylä-Herttuala S, Tanila H, Levonen AL, Koistinaho M, Koistinaho J. Kanninen K, et al. Among authors: malm t. Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16505-10. doi: 10.1073/pnas.0908397106. Epub 2009 Sep 10. Proc Natl Acad Sci U S A. 2009. PMID: 19805328 Free PMC article.
215 results