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Oral Treatment with Iododiflunisal Delays Hippocampal Amyloid-β Formation in a Transgenic Mouse Model of Alzheimer's Disease: A Longitudinal in vivo Molecular Imaging Study1.
Rejc L, Gómez-Vallejo V, Rios X, Cossío U, Baz Z, Mujica E, Gião T, Cotrina EY, Jiménez-Barbero J, Quintana J, Arsequell G, Cardoso I, Llop J. Rejc L, et al. Among authors: quintana j. J Alzheimers Dis. 2020;77(1):99-112. doi: 10.3233/JAD-200570. J Alzheimers Dis. 2020. PMID: 32804152
Insights on the Interaction between Transthyretin and Aβ in Solution. A Saturation Transfer Difference (STD) NMR Analysis of the Role of Iododiflunisal.
Gimeno A, Santos LM, Alemi M, Rivas J, Blasi D, Cotrina EY, Llop J, Valencia G, Cardoso I, Quintana J, Arsequell G, Jiménez-Barbero J. Gimeno A, et al. Among authors: quintana j. J Med Chem. 2017 Jul 13;60(13):5749-5758. doi: 10.1021/acs.jmedchem.7b00428. Epub 2017 Jun 16. J Med Chem. 2017. PMID: 28587455
Radiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for AD.
Rios X, Gómez-Vallejo V, Martín A, Cossío U, Morcillo MÁ, Alemi M, Cardoso I, Quintana J, Jiménez-Barbero J, Cotrina EY, Valencia G, Arsequell G, Llop J. Rios X, et al. Among authors: quintana j. Sci Rep. 2019 Sep 20;9(1):13672. doi: 10.1038/s41598-019-50071-w. Sci Rep. 2019. PMID: 31541162 Free PMC article.
Calorimetric Studies of Binary and Ternary Molecular Interactions between Transthyretin, Aβ Peptides, and Small-Molecule Chaperones toward an Alternative Strategy for Alzheimer's Disease Drug Discovery.
Cotrina EY, Gimeno A, Llop J, Jiménez-Barbero J, Quintana J, Valencia G, Cardoso I, Prohens R, Arsequell G. Cotrina EY, et al. Among authors: quintana j. J Med Chem. 2020 Mar 26;63(6):3205-3214. doi: 10.1021/acs.jmedchem.9b01970. Epub 2020 Mar 18. J Med Chem. 2020. PMID: 32124607 Free PMC article.
935 results