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A DNA Hypomethylating Drug Alters the Tumor Microenvironment and Improves the Effectiveness of Immune Checkpoint Inhibitors in a Mouse Model of Pancreatic Cancer.
Gonda TA, Fang J, Salas M, Do C, Hsu E, Zhukovskaya A, Siegel A, Takahashi R, Lopez-Bujanda ZA, Drake CG, Manji GA, Wang TC, Olive KP, Tycko B. Gonda TA, et al. Among authors: lopez bujanda za. Cancer Res. 2020 Nov 1;80(21):4754-4767. doi: 10.1158/0008-5472.CAN-20-0285. Epub 2020 Aug 14. Cancer Res. 2020. PMID: 32816859 Free PMC article.
Blocking IL1 Beta Promotes Tumor Regression and Remodeling of the Myeloid Compartment in a Renal Cell Carcinoma Model: Multidimensional Analyses.
Aggen DH, Ager CR, Obradovic AZ, Chowdhury N, Ghasemzadeh A, Mao W, Chaimowitz MG, Lopez-Bujanda ZA, Spina CS, Hawley JE, Dallos MC, Zhang C, Wang V, Li H, Guo XV, Drake CG. Aggen DH, et al. Among authors: lopez bujanda za. Clin Cancer Res. 2021 Jan 15;27(2):608-621. doi: 10.1158/1078-0432.CCR-20-1610. Epub 2020 Nov 4. Clin Cancer Res. 2021. PMID: 33148676 Free PMC article.
Stereotactic Radiotherapy Increases Functionally Suppressive Regulatory T Cells in the Tumor Microenvironment.
Muroyama Y, Nirschl TR, Kochel CM, Lopez-Bujanda Z, Theodros D, Mao W, Carrera-Haro MA, Ghasemzadeh A, Marciscano AE, Velarde E, Tam AJ, Thoburn CJ, Uddin M, Meeker AK, Anders RA, Pardoll DM, Drake CG. Muroyama Y, et al. Cancer Immunol Res. 2017 Nov;5(11):992-1004. doi: 10.1158/2326-6066.CIR-17-0040. Epub 2017 Oct 2. Cancer Immunol Res. 2017. PMID: 28970196 Free PMC article.
Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model.
Shen YC, Ghasemzadeh A, Kochel CM, Nirschl TR, Francica BJ, Lopez-Bujanda ZA, Carrera Haro MA, Tam A, Anders RA, Selby MJ, Korman AJ, Drake CG. Shen YC, et al. Among authors: lopez bujanda za. Prostate Cancer Prostatic Dis. 2018 Apr;21(1):113-125. doi: 10.1038/s41391-017-0013-x. Epub 2017 Dec 4. Prostate Cancer Prostatic Dis. 2018. PMID: 29203894 Free PMC article.
Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression.
Lopez-Bujanda ZA, Haffner MC, Chaimowitz MG, Chowdhury N, Venturini NJ, Patel RA, Obradovic A, Hansen CS, Jacków J, Maynard JP, Sfanos KS, Abate-Shen C, Bieberich CJ, Hurley PJ, Selby MJ, Korman AJ, Christiano AM, De Marzo AM, Drake CG. Lopez-Bujanda ZA, et al. Nat Cancer. 2021 Aug;2(8):803-818. doi: 10.1038/s43018-021-00227-3. Epub 2021 Jul 19. Nat Cancer. 2021. PMID: 35122025 Free PMC article.
TGM4: an immunogenic prostate-restricted antigen.
Lopez-Bujanda ZA, Obradovic A, Nirschl TR, Crowley L, Macedo R, Papachristodoulou A, O'Donnell T, Laserson U, Zarif JC, Reshef R, Yuan T, Soni MK, Antonarakis ES, Haffner MC, Larman HB, Shen MM, Muranski P, Drake CG. Lopez-Bujanda ZA, et al. J Immunother Cancer. 2021 Jun;9(6):e001649. doi: 10.1136/jitc-2020-001649. J Immunother Cancer. 2021. PMID: 34193566 Free PMC article.
Association between immunosuppressive cytokines and PSA progression in biochemically recurrent prostate cancer treated with intermittent hormonal therapy.
Hawley JE, Pan S, Figg WD, Lopez-Bujanda ZA, Strope JD, Aggen DH, Dallos MC, Lim EA, Stein MN, Hu J, Drake CG. Hawley JE, et al. Among authors: lopez bujanda za. Prostate. 2020 Mar;80(4):336-344. doi: 10.1002/pros.23948. Epub 2020 Jan 3. Prostate. 2020. PMID: 31899823 Free PMC article. Clinical Trial.
Cooperation of loss of NKX3.1 and inflammation in prostate cancer initiation.
Le Magnen C, Virk RK, Dutta A, Kim JY, Panja S, Lopez-Bujanda ZA, Califano A, Drake CG, Mitrofanova A, Abate-Shen C. Le Magnen C, et al. Among authors: lopez bujanda za. Dis Model Mech. 2018 Nov 16;11(11):dmm035139. doi: 10.1242/dmm.035139. Dis Model Mech. 2018. PMID: 30266798 Free PMC article.
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