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Response to trametinib treatment in progressive pediatric low-grade glioma patients.
Selt F, van Tilburg CM, Bison B, Sievers P, Harting I, Ecker J, Pajtler KW, Sahm F, Bahr A, Simon M, Jones DTW, Well L, Mautner VF, Capper D, Hernáiz Driever P, Gnekow A, Pfister SM, Witt O, Milde T. Selt F, et al. Among authors: ecker j. J Neurooncol. 2020 Sep;149(3):499-510. doi: 10.1007/s11060-020-03640-3. Epub 2020 Oct 7. J Neurooncol. 2020. PMID: 33026636 Free PMC article.
Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.
Ecker J, Oehme I, Mazitschek R, Korshunov A, Kool M, Hielscher T, Kiss J, Selt F, Konrad C, Lodrini M, Deubzer HE, von Deimling A, Kulozik AE, Pfister SM, Witt O, Milde T. Ecker J, et al. Acta Neuropathol Commun. 2015 Apr 3;3:22. doi: 10.1186/s40478-015-0201-7. Acta Neuropathol Commun. 2015. PMID: 25853389 Free PMC article.
Pediatric Targeted Therapy: Clinical Feasibility of Personalized Diagnostics in Children with Relapsed and Progressive Tumors.
Selt F, Deiß A, Korshunov A, Capper D, Witt H, van Tilburg CM, Jones DT, Witt R, Sahm F, Reuss D, Kölsche C, Ecker J, Oehme I, Hielscher T, von Deimling A, Kulozik AE, Pfister SM, Witt O, Milde T. Selt F, et al. Among authors: ecker j. Brain Pathol. 2016 Jul;26(4):506-16. doi: 10.1111/bpa.12326. Epub 2015 Nov 26. Brain Pathol. 2016. PMID: 26445087 Free PMC article.
Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing.
Selt F, Hohloch J, Hielscher T, Sahm F, Capper D, Korshunov A, Usta D, Brabetz S, Ridinger J, Ecker J, Oehme I, Gronych J, Marquardt V, Pauck D, Bächli H, Stiles CD, von Deimling A, Remke M, Schuhmann MU, Pfister SM, Brummer T, Jones DT, Witt O, Milde T. Selt F, et al. Among authors: ecker j. Oncotarget. 2017 Feb 14;8(7):11460-11479. doi: 10.18632/oncotarget.14004. Oncotarget. 2017. PMID: 28002790 Free PMC article.
Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations.
Koelsche C, Mynarek M, Schrimpf D, Bertero L, Serrano J, Sahm F, Reuss DE, Hou Y, Baumhoer D, Vokuhl C, Flucke U, Petersen I, Brück W, Rutkowski S, Zambrano SC, Garcia Leon JL, Diaz Coronado RY, Gessler M, Tirado OM, Mora J, Alonso J, Garcia Del Muro X, Esteller M, Sturm D, Ecker J, Milde T, Pfister SM, Korshunov A, Snuderl M, Mechtersheimer G, Schüller U, Jones DTW, von Deimling A. Koelsche C, et al. Among authors: ecker j. Acta Neuropathol. 2018 Aug;136(2):327-337. doi: 10.1007/s00401-018-1871-6. Epub 2018 Jun 7. Acta Neuropathol. 2018. PMID: 29881993 Free article.
Molecular Diagnostics in Pediatric Brain Tumors: Impact on Diagnosis and Clinical Decision-Making - A Selected Case Series.
Bächli H, Ecker J, van Tilburg C, Sturm D, Selt F, Sahm F, Koelsche C, Grund K, Sutter C, Pietsch T, Witt H, Herold-Mende C, von Deimling A, Jones D, Pfister S, Witt O, Milde T. Bächli H, et al. Among authors: ecker j. Klin Padiatr. 2018 Oct;230(6):305-313. doi: 10.1055/a-0637-9653. Epub 2018 Jul 11. Klin Padiatr. 2018. PMID: 29996150 English.
The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma.
Buhl JL, Selt F, Hielscher T, Guiho R, Ecker J, Sahm F, Ridinger J, Riehl D, Usta D, Ismer B, Sommerkamp AC, Martinez-Barbera JP, Wefers AK, Remke M, Picard D, Pusch S, Gronych J, Oehme I, van Tilburg CM, Kool M, Kuhn D, Capper D, von Deimling A, Schuhmann MU, Herold-Mende C, Korshunov A, Brummer T, Pfister SM, Jones DTW, Witt O, Milde T. Buhl JL, et al. Among authors: ecker j. Clin Cancer Res. 2019 Mar 15;25(6):1851-1866. doi: 10.1158/1078-0432.CCR-18-1965. Epub 2018 Dec 7. Clin Cancer Res. 2019. PMID: 30530705
Retinoblastoma with late metastatic spread-a case report.
Hofer S, Diebold J, Temming P, Lohmann D, Howell J, Moulin A, Beck-Popovic M, Sahm F, Milde T, Ecker J. Hofer S, et al. Among authors: ecker j. Pediatr Blood Cancer. 2019 Jun;66(6):e27656. doi: 10.1002/pbc.27656. Epub 2019 Feb 5. Pediatr Blood Cancer. 2019. PMID: 30724037 No abstract available.
Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions.
Stichel D, Schrimpf D, Casalini B, Meyer J, Wefers AK, Sievers P, Korshunov A, Koelsche C, Reuss DE, Reinhardt A, Ebrahimi A, Fernández-Klett F, Kessler T, Sturm D, Ecker J, Milde T, Herold-Mende C, Witt O, Pfister SM, Wick W, Jones DTW, von Deimling A, Sahm F. Stichel D, et al. Among authors: ecker j. Acta Neuropathol. 2019 Nov;138(5):827-835. doi: 10.1007/s00401-019-02039-3. Epub 2019 Jul 5. Acta Neuropathol. 2019. PMID: 31278449
678 results