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Response to trametinib treatment in progressive pediatric low-grade glioma patients.
Selt F, van Tilburg CM, Bison B, Sievers P, Harting I, Ecker J, Pajtler KW, Sahm F, Bahr A, Simon M, Jones DTW, Well L, Mautner VF, Capper D, Hernáiz Driever P, Gnekow A, Pfister SM, Witt O, Milde T. Selt F, et al. Among authors: gnekow a. J Neurooncol. 2020 Sep;149(3):499-510. doi: 10.1007/s11060-020-03640-3. Epub 2020 Oct 7. J Neurooncol. 2020. PMID: 33026636 Free PMC article.
BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas.
Pfister S, Janzarik WG, Remke M, Ernst A, Werft W, Becker N, Toedt G, Wittmann A, Kratz C, Olbrich H, Ahmadi R, Thieme B, Joos S, Radlwimmer B, Kulozik A, Pietsch T, Herold-Mende C, Gnekow A, Reifenberger G, Korshunov A, Scheurlen W, Omran H, Lichter P. Pfister S, et al. Among authors: gnekow a. J Clin Invest. 2008 May;118(5):1739-49. doi: 10.1172/JCI33656. J Clin Invest. 2008. PMID: 18398503 Free PMC article.
Treatment of early childhood medulloblastoma by postoperative chemotherapy and deferred radiotherapy.
Rutkowski S, Gerber NU, von Hoff K, Gnekow A, Bode U, Graf N, Berthold F, Henze G, Wolff JE, Warmuth-Metz M, Soerensen N, Emser A, Ottensmeier H, Deinlein F, Schlegel PG, Kortmann RD, Pietsch T, Kuehl J; German Pediatric Brain Tumor Study Group. Rutkowski S, et al. Among authors: gnekow a. Neuro Oncol. 2009 Apr;11(2):201-10. doi: 10.1215/15228517-2008-084. Epub 2008 Sep 25. Neuro Oncol. 2009. PMID: 18818397 Free PMC article.
Natural history and management of low-grade glioma in NF-1 children.
Hernáiz Driever P, von Hornstein S, Pietsch T, Kortmann R, Warmuth-Metz M, Emser A, Gnekow AK. Hernáiz Driever P, et al. Among authors: gnekow ak. J Neurooncol. 2010 Nov;100(2):199-207. doi: 10.1007/s11060-010-0159-z. Epub 2010 Mar 30. J Neurooncol. 2010. PMID: 20352473 Clinical Trial.
Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma.
Cin H, Meyer C, Herr R, Janzarik WG, Lambert S, Jones DT, Jacob K, Benner A, Witt H, Remke M, Bender S, Falkenstein F, Van Anh TN, Olbrich H, von Deimling A, Pekrun A, Kulozik AE, Gnekow A, Scheurlen W, Witt O, Omran H, Jabado N, Collins VP, Brummer T, Marschalek R, Lichter P, Korshunov A, Pfister SM. Cin H, et al. Among authors: gnekow a. Acta Neuropathol. 2011 Jun;121(6):763-74. doi: 10.1007/s00401-011-0817-z. Epub 2011 Mar 20. Acta Neuropathol. 2011. PMID: 21424530
Thalamic high-grade gliomas in children: a distinct clinical subset?
Kramm CM, Butenhoff S, Rausche U, Warmuth-Metz M, Kortmann RD, Pietsch T, Gnekow A, Jorch N, Janssen G, Berthold F, Wolff JE. Kramm CM, et al. Among authors: gnekow a. Neuro Oncol. 2011 Jun;13(6):680-9. doi: 10.1093/neuonc/nor045. Neuro Oncol. 2011. PMID: 21636712 Free PMC article.
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