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Page 1
Response to trametinib treatment in progressive pediatric low-grade glioma patients.
Selt F, van Tilburg CM, Bison B, Sievers P, Harting I, Ecker J, Pajtler KW, Sahm F, Bahr A, Simon M, Jones DTW, Well L, Mautner VF, Capper D, Hernáiz Driever P, Gnekow A, Pfister SM, Witt O, Milde T. Selt F, et al. Among authors: sievers p. J Neurooncol. 2020 Sep;149(3):499-510. doi: 10.1007/s11060-020-03640-3. Epub 2020 Oct 7. J Neurooncol. 2020. PMID: 33026636 Free PMC article.
CNS neuroblastoma, FOXR2-activated and its mimics: a relevant panel approach for work-up and accurate diagnosis of this rare neoplasm.
Tauziède-Espariat A, Figarella-Branger D, Métais A, Uro-Coste E, Maurage CA, Lhermitte B, Aline-Fardin A, Hasty L, Vasiljevic A, Chiforeanu D, Chotard G, Adle-Biassette H, Meurgey A, Saffroy R, Guillemot D, Pierron G, Sievers P, Varlet P; the RENOCLIP-LOC. Tauziède-Espariat A, et al. Among authors: sievers p. Acta Neuropathol Commun. 2023 Mar 14;11(1):43. doi: 10.1186/s40478-023-01536-7. Acta Neuropathol Commun. 2023. PMID: 36918978 Free PMC article. No abstract available.
Novel, improved grading system(s) for IDH-mutant astrocytic gliomas.
Shirahata M, Ono T, Stichel D, Schrimpf D, Reuss DE, Sahm F, Koelsche C, Wefers A, Reinhardt A, Huang K, Sievers P, Shimizu H, Nanjo H, Kobayashi Y, Miyake Y, Suzuki T, Adachi JI, Mishima K, Sasaki A, Nishikawa R, Bewerunge-Hudler M, Ryzhova M, Absalyamova O, Golanov A, Sinn P, Platten M, Jungk C, Winkler F, Wick A, Hänggi D, Unterberg A, Pfister SM, Jones DTW, van den Bent M, Hegi M, French P, Baumert BG, Stupp R, Gorlia T, Weller M, Capper D, Korshunov A, Herold-Mende C, Wick W, Louis DN, von Deimling A. Shirahata M, et al. Among authors: sievers p. Acta Neuropathol. 2018 Jul;136(1):153-166. doi: 10.1007/s00401-018-1849-4. Epub 2018 Apr 23. Acta Neuropathol. 2018. PMID: 29687258 Free article.
Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience.
Capper D, Stichel D, Sahm F, Jones DTW, Schrimpf D, Sill M, Schmid S, Hovestadt V, Reuss DE, Koelsche C, Reinhardt A, Wefers AK, Huang K, Sievers P, Ebrahimi A, Schöler A, Teichmann D, Koch A, Hänggi D, Unterberg A, Platten M, Wick W, Witt O, Milde T, Korshunov A, Pfister SM, von Deimling A. Capper D, et al. Among authors: sievers p. Acta Neuropathol. 2018 Aug;136(2):181-210. doi: 10.1007/s00401-018-1879-y. Epub 2018 Jul 2. Acta Neuropathol. 2018. PMID: 29967940 Free PMC article.
FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma.
Sievers P, Stichel D, Schrimpf D, Sahm F, Koelsche C, Reuss DE, Wefers AK, Reinhardt A, Huang K, Ebrahimi A, Hou Y, Pajtler KW, Pfister SM, Hasselblatt M, Stummer W, Schick U, Hartmann C, Hagel C, Staszewski O, Reifenberger G, Beschorner R, Coras R, Keyvani K, Kohlhof P, Diomedi-Camassei F, Herold-Mende C, Giangaspero F, Rushing E, Giannini C, Korshunov A, Jones DTW, von Deimling A. Sievers P, et al. Acta Neuropathol. 2018 Aug;136(2):293-302. doi: 10.1007/s00401-018-1882-3. Epub 2018 Jul 5. Acta Neuropathol. 2018. PMID: 29978331
Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p.
Sievers P, Stichel D, Hielscher T, Schrimpf D, Reinhardt A, Wefers AK, Reuss D, Jones DTW, Bewerunge-Hudler M, Hartmann C, Baumgarten P, Wirsching HG, Winther-Kristensen B, Brokinkel B, Ketter R, Idoate Gastearena MA, Lamszus K, Seiz-Rosenhagen M, Mawrin C, Harter PN, Felsberg J, Hänggi D, Herold-Mende C, Berghoff AS, Weller M, Pfister SM, Wick W, Reifenberger G, Preusser M, von Deimling A, Sahm F. Sievers P, et al. Acta Neuropathol. 2018 Dec;136(6):975-978. doi: 10.1007/s00401-018-1924-x. Epub 2018 Oct 31. Acta Neuropathol. 2018. PMID: 30382370 Free article. No abstract available.
Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA.
Hou Y, Pinheiro J, Sahm F, Reuss DE, Schrimpf D, Stichel D, Casalini B, Koelsche C, Sievers P, Wefers AK, Reinhardt A, Ebrahimi A, Fernández-Klett F, Pusch S, Meier J, Schweizer L, Paulus W, Prinz M, Hartmann C, Plate KH, Reifenberger G, Pietsch T, Varlet P, Pagès M, Schüller U, Scheie D, de Stricker K, Frank S, Hench J, Pollo B, Brandner S, Unterberg A, Pfister SM, Jones DTW, Korshunov A, Wick W, Capper D, Blümcke I, von Deimling A, Bertero L. Hou Y, et al. Among authors: sievers p. Acta Neuropathol. 2019 May;137(5):837-846. doi: 10.1007/s00401-019-01969-2. Epub 2019 Feb 13. Acta Neuropathol. 2019. PMID: 30759284
Desmoplastic/nodular medulloblastomas (DNMB) and medulloblastomas with extensive nodularity (MBEN) disclose similar epigenetic signatures but different transcriptional profiles.
Korshunov A, Sahm F, Okonechnikov K, Ryzhova M, Stichel D, Schrimpf D, Casalini B, Sievers P, Meyer J, Zheludkova O, Golanov A, Lichter P, Jones DTW, Pfister SM, Kool M, von Deimling A. Korshunov A, et al. Among authors: sievers p. Acta Neuropathol. 2019 Jun;137(6):1003-1015. doi: 10.1007/s00401-019-01981-6. Epub 2019 Mar 2. Acta Neuropathol. 2019. PMID: 30826918
Molecular progression of SHH-activated medulloblastomas.
Korshunov A, Okonechnikov K, Sahm F, Ryzhova M, Stichel D, Sievers P, Meyer J, Schrimpf D, Zheludkova O, Golanov A, Lichter P, Jones DTW, Pfister SM, von Deimling A, Kool M. Korshunov A, et al. Among authors: sievers p. Acta Neuropathol. 2019 Aug;138(2):327-330. doi: 10.1007/s00401-019-02022-y. Epub 2019 Apr 27. Acta Neuropathol. 2019. PMID: 31030238 No abstract available.
Mutational patterns and regulatory networks in epigenetic subgroups of meningioma.
Paramasivam N, Hübschmann D, Toprak UH, Ishaque N, Neidert M, Schrimpf D, Stichel D, Reuss D, Sievers P, Reinhardt A, Wefers AK, Jones DTW, Gu Z, Werner J, Uhrig S, Wirsching HG, Schick M, Bewerunge-Hudler M, Beck K, Brehmer S, Urbschat S, Seiz-Rosenhagen M, Hänggi D, Herold-Mende C, Ketter R, Eils R, Ram Z, Pfister SM, Wick W, Weller M, Grossmann R, von Deimling A, Schlesner M, Sahm F. Paramasivam N, et al. Among authors: sievers p. Acta Neuropathol. 2019 Aug;138(2):295-308. doi: 10.1007/s00401-019-02008-w. Epub 2019 May 8. Acta Neuropathol. 2019. PMID: 31069492
118 results