Sheppard D - Search Results

1

Gli1⁺ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung.

Cassandras M, Wang C, Kathiriya J, Tsukui T, Matatia P, Matthay M, Wolters P, Molofsky A, Sheppard D, Chapman H, Peng T. Cassandras M, et al. Among authors: sheppard d. Nat Cell Biol. 2020 Nov;22(11):1295-1306. doi: 10.1038/s41556-020-00591-9. Epub 2020 Oct 12. Nat Cell Biol. 2020. PMID: 33046884 Free PMC article.

2

The alpha v beta 6 integrin promotes proliferation of colon carcinoma cells through a unique region of the beta 6 cytoplasmic domain.

Agrez M, Chen A, Cone RI, Pytela R, Sheppard D. Agrez M, et al. Among authors: sheppard d. J Cell Biol. 1994 Oct;127(2):547-56. doi: 10.1083/jcb.127.2.547. J Cell Biol. 1994. PMID: 7929593 Free PMC article.

3

Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin.

Huang XZ, Wu JF, Cass D, Erle DJ, Corry D, Young SG, Farese RV Jr, Sheppard D. Huang XZ, et al. Among authors: sheppard d. J Cell Biol. 1996 May;133(4):921-8. doi: 10.1083/jcb.133.4.921. J Cell Biol. 1996. PMID: 8666675 Free PMC article.

4

Airway epithelial integrins: why so many?

Sheppard D. Sheppard D. Am J Respir Cell Mol Biol. 1998 Sep;19(3):349-51. doi: 10.1165/ajrcmb.19.3.f144. Am J Respir Cell Mol Biol. 1998. PMID: 9730861 No abstract available.

5

The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis.

Munger JS, Huang X, Kawakatsu H, Griffiths MJ, Dalton SL, Wu J, Pittet JF, Kaminski N, Garat C, Matthay MA, Rifkin DB, Sheppard D. Munger JS, et al. Among authors: sheppard d. Cell. 1999 Feb 5;96(3):319-28. doi: 10.1016/s0092-8674(00)80545-0. Cell. 1999. PMID: 10025398 Free article.

6

The integrin alpha9beta1 mediates adhesion to activated endothelial cells and transendothelial neutrophil migration through interaction with vascular cell adhesion molecule-1.

Taooka Y, Chen J, Yednock T, Sheppard D. Taooka Y, et al. Among authors: sheppard d. J Cell Biol. 1999 Apr 19;145(2):413-20. doi: 10.1083/jcb.145.2.413. J Cell Biol. 1999. PMID: 10209034 Free PMC article.

7

TGF-beta is a critical mediator of acute lung injury.

Pittet JF, Griffiths MJ, Geiser T, Kaminski N, Dalton SL, Huang X, Brown LA, Gotwals PJ, Koteliansky VE, Matthay MA, Sheppard D. Pittet JF, et al. Among authors: sheppard d. J Clin Invest. 2001 Jun;107(12):1537-44. doi: 10.1172/JCI11963. J Clin Invest. 2001. PMID: 11413161 Free PMC article.

8

Transforming growth factor-beta1 decreases expression of the epithelial sodium channel alphaENaC and alveolar epithelial vectorial sodium and fluid transport via an ERK1/2-dependent mechanism.

Frank J, Roux J, Kawakatsu H, Su G, Dagenais A, Berthiaume Y, Howard M, Canessa CM, Fang X, Sheppard D, Matthay MA, Pittet JF. Frank J, et al. Among authors: sheppard d. J Biol Chem. 2003 Nov 7;278(45):43939-50. doi: 10.1074/jbc.M304882200. Epub 2003 Aug 20. J Biol Chem. 2003. PMID: 12930837 Free article.

9

Interleukin-1beta decreases expression of the epithelial sodium channel alpha-subunit in alveolar epithelial cells via a p38 MAPK-dependent signaling pathway.

Roux J, Kawakatsu H, Gartland B, Pespeni M, Sheppard D, Matthay MA, Canessa CM, Pittet JF. Roux J, et al. Among authors: sheppard d. J Biol Chem. 2005 May 13;280(19):18579-89. doi: 10.1074/jbc.M410561200. Epub 2005 Mar 8. J Biol Chem. 2005. PMID: 15755725 Free article.

10

Mfge8 is critical for mammary gland remodeling during involution.

Atabai K, Fernandez R, Huang X, Ueki I, Kline A, Li Y, Sadatmansoori S, Smith-Steinhart C, Zhu W, Pytela R, Werb Z, Sheppard D. Atabai K, et al. Among authors: sheppard d. Mol Biol Cell. 2005 Dec;16(12):5528-37. doi: 10.1091/mbc.e05-02-0128. Epub 2005 Sep 29. Mol Biol Cell. 2005. PMID: 16195353 Free PMC article.

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