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Multi-Tissue Acceleration of the Mitochondrial Phosphoenolpyruvate Cycle Improves Whole-Body Metabolic Health.
Abulizi A, Cardone RL, Stark R, Lewandowski SL, Zhao X, Hillion J, Ma L, Sehgal R, Alves TC, Thomas C, Kung C, Wang B, Siebel S, Andrews ZB, Mason GF, Rinehart J, Merrins MJ, Kibbey RG. Abulizi A, et al. Among authors: merrins mj. Cell Metab. 2020 Nov 3;32(5):751-766.e11. doi: 10.1016/j.cmet.2020.10.006. Cell Metab. 2020. PMID: 33147485 Free PMC article.
Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health.
Fontana L, Cummings NE, Arriola Apelo SI, Neuman JC, Kasza I, Schmidt BA, Cava E, Spelta F, Tosti V, Syed FA, Baar EL, Veronese N, Cottrell SE, Fenske RJ, Bertozzi B, Brar HK, Pietka T, Bullock AD, Figenshau RS, Andriole GL, Merrins MJ, Alexander CM, Kimple ME, Lamming DW. Fontana L, et al. Among authors: merrins mj. Cell Rep. 2016 Jul 12;16(2):520-530. doi: 10.1016/j.celrep.2016.05.092. Epub 2016 Jun 23. Cell Rep. 2016. PMID: 27346343 Free PMC article. Clinical Trial.
β Cell tone is defined by proglucagon peptides through cAMP signaling.
Capozzi ME, Svendsen B, Encisco SE, Lewandowski SL, Martin MD, Lin H, Jaffe JL, Coch RW, Haldeman JM, MacDonald PE, Merrins MJ, D'Alessio DA, Campbell JE. Capozzi ME, et al. Among authors: merrins mj. JCI Insight. 2019 Mar 7;4(5):e126742. doi: 10.1172/jci.insight.126742. eCollection 2019 Mar 7. JCI Insight. 2019. PMID: 30720465 Free PMC article.
Pyruvate Kinase Controls Signal Strength in the Insulin Secretory Pathway.
Lewandowski SL, Cardone RL, Foster HR, Ho T, Potapenko E, Poudel C, VanDeusen HR, Sdao SM, Alves TC, Zhao X, Capozzi ME, de Souza AH, Jahan I, Thomas CJ, Nunemaker CS, Davis DB, Campbell JE, Kibbey RG, Merrins MJ. Lewandowski SL, et al. Among authors: merrins mj. Cell Metab. 2020 Nov 3;32(5):736-750.e5. doi: 10.1016/j.cmet.2020.10.007. Cell Metab. 2020. PMID: 33147484 Free PMC article.
β Cell-specific deletion of Zfp148 improves nutrient-stimulated β cell Ca2+ responses.
Emfinger CH, de Klerk E, Schueler KL, Rabaglia ME, Stapleton DS, Simonett SP, Mitok KA, Wang Z, Liu X, Paulo JA, Yu Q, Cardone RL, Foster HR, Lewandowski SL, Perales JC, Kendziorski CM, Gygi SP, Kibbey RG, Keller MP, Hebrok M, Merrins MJ, Attie AD. Emfinger CH, et al. Among authors: merrins mj. JCI Insight. 2022 May 23;7(10):e154198. doi: 10.1172/jci.insight.154198. JCI Insight. 2022. PMID: 35603790 Free PMC article.
Metabolic cycles and signals for insulin secretion.
Merrins MJ, Corkey BE, Kibbey RG, Prentki M. Merrins MJ, et al. Cell Metab. 2022 Jul 5;34(7):947-968. doi: 10.1016/j.cmet.2022.06.003. Epub 2022 Jun 20. Cell Metab. 2022. PMID: 35728586 Free PMC article. Review.
48 results