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GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils.
Gibbons GS, Banks RA, Kim B, Xu H, Changolkar L, Leight SN, Riddle DM, Li C, Gathagan RJ, Brown HJ, Zhang B, Trojanowski JQ, Lee VM. Gibbons GS, et al. J Neurosci. 2017 Nov 22;37(47):11485-11494. doi: 10.1523/JNEUROSCI.2393-17.2017. Epub 2017 Oct 6. J Neurosci. 2017. PMID: 28986461 Free PMC article.
Transmission of tauopathy strains is independent of their isoform composition.
He Z, McBride JD, Xu H, Changolkar L, Kim SJ, Zhang B, Narasimhan S, Gibbons GS, Guo JL, Kozak M, Schellenberg GD, Trojanowski JQ, Lee VM. He Z, et al. Among authors: gibbons gs. Nat Commun. 2020 Jan 7;11(1):7. doi: 10.1038/s41467-019-13787-x. Nat Commun. 2020. PMID: 31911587 Free PMC article.
Degeneration of the locus coeruleus is a common feature of tauopathies and distinct from TDP-43 proteinopathies in the frontotemporal lobar degeneration spectrum.
Ohm DT, Peterson C, Lobrovich R, Cousins KAQ, Gibbons GS, McMillan CT, Wolk DA, Van Deerlin V, Elman L, Spindler M, Deik A, Siderowf A, Trojanowski JQ, Lee EB, Grossman M, Irwin DJ. Ohm DT, et al. Among authors: gibbons gs. Acta Neuropathol. 2020 Nov;140(5):675-693. doi: 10.1007/s00401-020-02210-1. Epub 2020 Aug 17. Acta Neuropathol. 2020. PMID: 32804255 Free PMC article.
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