Javitch JA - Search Results

1

A non-helical region in transmembrane helix 6 of hydrophobic amino acid transporter MhsT mediates substrate recognition.

Focht D, Neumann C, Lyons J, Eguskiza Bilbao A, Blunck R, Malinauskaite L, Schwarz IO, Javitch JA, Quick M, Nissen P. Focht D, et al. Among authors: javitch ja. EMBO J. 2021 Jan 4;40(1):e105164. doi: 10.15252/embj.2020105164. Epub 2020 Nov 6. EMBO J. 2021. PMID: 33155685 Free PMC article.

2

How did the neurotransmitter cross the bilayer? A closer view.

Sonders MS, Quick M, Javitch JA. Sonders MS, et al. Among authors: javitch ja. Curr Opin Neurobiol. 2005 Jun;15(3):296-304. doi: 10.1016/j.conb.2005.05.009. Curr Opin Neurobiol. 2005. PMID: 15919190 Review.

3

Intramolecular cross-linking in a bacterial homolog of mammalian SLC6 neurotransmitter transporters suggests an evolutionary conserved role of transmembrane segments 7 and 8.

Kniazeff J, Loland CJ, Goldberg N, Quick M, Das S, Sitte HH, Javitch JA, Gether U. Kniazeff J, et al. Among authors: javitch ja. Neuropharmacology. 2005 Nov;49(6):715-23. doi: 10.1016/j.neuropharm.2005.07.003. Epub 2005 Aug 29. Neuropharmacology. 2005. PMID: 16129457

4

State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum.

Quick M, Yano H, Goldberg NR, Duan L, Beuming T, Shi L, Weinstein H, Javitch JA. Quick M, et al. Among authors: javitch ja. J Biol Chem. 2006 Sep 8;281(36):26444-54. doi: 10.1074/jbc.M602438200. Epub 2006 Jun 23. J Biol Chem. 2006. PMID: 16798738 Free article.

5

Monitoring the function of membrane transport proteins in detergent-solubilized form.

Quick M, Javitch JA. Quick M, et al. Among authors: javitch ja. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3603-8. doi: 10.1073/pnas.0609573104. Epub 2007 Feb 20. Proc Natl Acad Sci U S A. 2007. PMID: 17360689 Free PMC article.

6

Mechanism of chloride interaction with neurotransmitter:sodium symporters.

Zomot E, Bendahan A, Quick M, Zhao Y, Javitch JA, Kanner BI. Zomot E, et al. Among authors: javitch ja. Nature. 2007 Oct 11;449(7163):726-30. doi: 10.1038/nature06133. Epub 2007 Aug 19. Nature. 2007. PMID: 17704762

7

The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site.

Shi L, Quick M, Zhao Y, Weinstein H, Javitch JA. Shi L, et al. Among authors: javitch ja. Mol Cell. 2008 Jun 20;30(6):667-77. doi: 10.1016/j.molcel.2008.05.008. Mol Cell. 2008. PMID: 18570870 Free PMC article.

8

Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation.

Quick M, Winther AM, Shi L, Nissen P, Weinstein H, Javitch JA. Quick M, et al. Among authors: javitch ja. Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5563-8. doi: 10.1073/pnas.0811322106. Epub 2009 Mar 23. Proc Natl Acad Sci U S A. 2009. PMID: 19307590 Free PMC article.

9

Substrate-dependent proton antiport in neurotransmitter:sodium symporters.

Zhao Y, Quick M, Shi L, Mehler EL, Weinstein H, Javitch JA. Zhao Y, et al. Among authors: javitch ja. Nat Chem Biol. 2010 Feb;6(2):109-16. doi: 10.1038/nchembio.284. Epub 2009 Dec 27. Nat Chem Biol. 2010. PMID: 20081826 Free PMC article.

10

Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters.

Claxton DP, Quick M, Shi L, de Carvalho FD, Weinstein H, Javitch JA, McHaourab HS. Claxton DP, et al. Among authors: javitch ja. Nat Struct Mol Biol. 2010 Jul;17(7):822-9. doi: 10.1038/nsmb.1854. Epub 2010 Jun 20. Nat Struct Mol Biol. 2010. PMID: 20562855 Free PMC article.

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