Dennahy IS - Search Results

1

Pharmacologic modulation of brain metabolism by valproic acid can induce a neuroprotective environment.

Bhatti UF, Karnovsky A, Dennahy IS, Kachman M, Williams AM, Nikolian VC, Biesterveld BE, Siddiqui A, O'Connell RL, Liu B, Li Y, Alam HB. Bhatti UF, et al. Among authors: dennahy is. J Trauma Acute Care Surg. 2021 Mar 1;90(3):507-514. doi: 10.1097/TA.0000000000003026. J Trauma Acute Care Surg. 2021. PMID: 33196629

2

Valproic acid decreases brain lesion size and improves neurologic recovery in swine subjected to traumatic brain injury, hemorrhagic shock, and polytrauma.

Nikolian VC, Georgoff PE, Pai MP, Dennahy IS, Chtraklin K, Eidy H, Ghandour MH, Han Y, Srinivasan A, Li Y, Alam HB. Nikolian VC, et al. Among authors: dennahy is. J Trauma Acute Care Surg. 2017 Dec;83(6):1066-1073. doi: 10.1097/TA.0000000000001612. J Trauma Acute Care Surg. 2017. PMID: 28697014

3

Improvement of Blood-Brain Barrier Integrity in Traumatic Brain Injury and Hemorrhagic Shock Following Treatment With Valproic Acid and Fresh Frozen Plasma.

Nikolian VC, Dekker SE, Bambakidis T, Higgins GA, Dennahy IS, Georgoff PE, Williams AM, Andjelkovic AV, Alam HB. Nikolian VC, et al. Among authors: dennahy is. Crit Care Med. 2018 Jan;46(1):e59-e66. doi: 10.1097/CCM.0000000000002800. Crit Care Med. 2018. PMID: 29095204

4

Transcriptomic changes following valproic acid treatment promote neurogenesis and minimize secondary brain injury.

Nikolian VC, Dennahy IS, Higgins GA, Williams AM, Weykamp M, Georgoff PE, Eidy H, Ghandour MH, Chang P, Alam HB. Nikolian VC, et al. Among authors: dennahy is. J Trauma Acute Care Surg. 2018 Mar;84(3):459-465. doi: 10.1097/TA.0000000000001765. J Trauma Acute Care Surg. 2018. PMID: 29251707 Free PMC article.

5

Histone deacetylase inhibitors: Isoform selectivity improves survival in a hemorrhagic shock model.

Chang P, Weykamp M, Dennahy IS, Williams AM, Bhatti UF, Liu B, Nikolian VC, Li Y, Alam HB. Chang P, et al. Among authors: dennahy is. J Trauma Acute Care Surg. 2018 May;84(5):795-801. doi: 10.1097/TA.0000000000001824. J Trauma Acute Care Surg. 2018. PMID: 29401190 Free PMC article.

6

Valproic Acid Treatment Decreases Serum Glial Fibrillary Acidic Protein and Neurofilament Light Chain Levels in Swine Subjected to Traumatic Brain Injury.

Korley FK, Nikolian VC, Williams AM, Dennahy IS, Weykamp M, Alam HB. Korley FK, et al. Among authors: dennahy is. J Neurotrauma. 2018 May 15;35(10):1185-1191. doi: 10.1089/neu.2017.5581. Epub 2018 Mar 13. J Neurotrauma. 2018. PMID: 29415612

7

Rapid valproic acid-induced modulation of the traumatic proteome in a porcine model of traumatic brain injury and hemorrhagic shock.

Weykamp M, Nikolian VC, Dennahy IS, Higgins GA, Georgoff PE, Remmer H, Ghandour MH, Alam HB. Weykamp M, et al. Among authors: dennahy is. J Surg Res. 2018 Aug;228:84-92. doi: 10.1016/j.jss.2018.02.046. Epub 2018 Apr 25. J Surg Res. 2018. PMID: 29907235

8

Isoform 6-selective histone deacetylase inhibition reduces lesion size and brain swelling following traumatic brain injury and hemorrhagic shock.

Nikolian VC, Dennahy IS, Weykamp M, Williams AM, Bhatti UF, Eidy H, Ghandour MH, Chtraklin K, Li Y, Alam HB. Nikolian VC, et al. Among authors: dennahy is. J Trauma Acute Care Surg. 2019 Feb;86(2):232-239. doi: 10.1097/TA.0000000000002119. J Trauma Acute Care Surg. 2019. PMID: 30399139

9

Inhibition of histone deacetylase 6 attenuates intestinal inflammation and apoptosis in a rodent model of hemorrhagic shock.

Chang P, Bhatti UF, Williams AM, Dennahy IS, Liu B, Li Y, Alam HB. Chang P, et al. Among authors: dennahy is. J Trauma Acute Care Surg. 2019 May;86(5):874-880. doi: 10.1097/TA.0000000000002169. J Trauma Acute Care Surg. 2019. PMID: 30562325

10

Histone Deacetylase Inhibitors: A Novel Strategy in Trauma and Sepsis.

Williams AM, Dennahy IS, Bhatti UF, Biesterveld BE, Graham NJ, Li Y, Alam HB. Williams AM, et al. Among authors: dennahy is. Shock. 2019 Sep;52(3):300-306. doi: 10.1097/SHK.0000000000001308. Shock. 2019. PMID: 30601405 Free PMC article. Review.

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