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Early single-dose treatment with exosomes provides neuroprotection and improves blood-brain barrier integrity in swine model of traumatic brain injury and hemorrhagic shock.
Williams AM, Bhatti UF, Brown JF, Biesterveld BE, Kathawate RG, Graham NJ, Chtraklin K, Siddiqui AZ, Dekker SE, Andjelkovic A, Higgins GA, Buller B, Alam HB. Williams AM, et al. Among authors: siddiqui az. J Trauma Acute Care Surg. 2020 Feb;88(2):207-218. doi: 10.1097/TA.0000000000002563. J Trauma Acute Care Surg. 2020. PMID: 31804413
Early single-dose exosome treatment improves neurologic outcomes in a 7-day swine model of traumatic brain injury and hemorrhagic shock.
Williams AM, Wu Z, Bhatti UF, Biesterveld BE, Kemp MT, Wakam GK, Vercruysse CA, Chtraklin K, Siddiqui AZ, Pickell Z, Dekker SE, Tian Y, Liu B, Li Y, Buller B, Alam HB. Williams AM, et al. Among authors: siddiqui az. J Trauma Acute Care Surg. 2020 Aug;89(2):388-396. doi: 10.1097/TA.0000000000002698. J Trauma Acute Care Surg. 2020. PMID: 32218019
Valproic acid treatment rescues injured tissues after traumatic brain injury.
Biesterveld BE, Pumiglia L, Iancu A, Shamshad AA, Remmer HA, Siddiqui AZ, O'Connell RL, Wakam GK, Kemp MT, Williams AM, Pai MP, Alam HB. Biesterveld BE, et al. Among authors: siddiqui az. J Trauma Acute Care Surg. 2020 Dec;89(6):1156-1165. doi: 10.1097/TA.0000000000002918. J Trauma Acute Care Surg. 2020. PMID: 32890344 Free PMC article.
Administration of valproic acid in clinically approved dose improves neurologic recovery and decreases brain lesion size in swine subjected to hemorrhagic shock and traumatic brain injury.
Wakam GK, Biesterveld BE, Pai MP, Kemp MT, O'Connell RL, Williams AM, Srinivasan A, Chtraklin K, Siddiqui AZ, Bhatti UF, Vercruysse CA, Alam HB. Wakam GK, et al. Among authors: siddiqui az. J Trauma Acute Care Surg. 2021 Feb 1;90(2):346-352. doi: 10.1097/TA.0000000000003036. J Trauma Acute Care Surg. 2021. PMID: 33230090
Valproic Acid Protects Against Acute Kidney Injury in Hemorrhage and Trauma.
Biesterveld BE, Siddiqui AZ, O'Connell RL, Remmer H, Williams AM, Shamshad A, Smith WM, Kemp MT, Wakam GK, Alam HB. Biesterveld BE, et al. Among authors: siddiqui az. J Surg Res. 2021 Oct;266:222-229. doi: 10.1016/j.jss.2021.04.014. Epub 2021 May 20. J Surg Res. 2021. PMID: 34023578 Free PMC article.
3,243 results