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The Development of a Novel Nanobody Therapeutic for SARS-CoV-2.
Ye G, Gallant JP, Massey C, Shi K, Tai W, Zheng J, Odle AE, Vickers MA, Shang J, Wan Y, Drelich A, Kempaiah KR, Tat V, Perlman S, Du L, Tseng CT, Aihara H, LeBeau AM, Li F. Ye G, et al. Among authors: aihara h. bioRxiv [Preprint]. 2020 Nov 17:2020.11.17.386532. doi: 10.1101/2020.11.17.386532. bioRxiv. 2020. Update in: Elife. 2021 Aug 02;10:e64815. doi: 10.7554/eLife.64815. PMID: 33236012 Free PMC article. Updated. Preprint.
Structural basis of receptor recognition by SARS-CoV-2.
Shang J, Ye G, Shi K, Wan Y, Luo C, Aihara H, Geng Q, Auerbach A, Li F. Shang J, et al. Among authors: aihara h. Nature. 2020 May;581(7807):221-224. doi: 10.1038/s41586-020-2179-y. Epub 2020 Mar 30. Nature. 2020. PMID: 32225175 Free PMC article.
The development of Nanosota-1 as anti-SARS-CoV-2 nanobody drug candidates.
Ye G, Gallant J, Zheng J, Massey C, Shi K, Tai W, Odle A, Vickers M, Shang J, Wan Y, Du L, Aihara H, Perlman S, LeBeau A, Li F. Ye G, et al. Among authors: aihara h. Elife. 2021 Aug 2;10:e64815. doi: 10.7554/eLife.64815. Elife. 2021. PMID: 34338634 Free PMC article.
Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography.
Ubah OC, Lake EW, Gunaratne GS, Gallant JP, Fernie M, Robertson AJ, Marchant JS, Bold TD, Langlois RA, Matchett WE, Thiede JM, Shi K, Yin L, Moeller NH, Banerjee S, Ferguson L, Kovaleva M, Porter AJ, Aihara H, LeBeau AM, Barelle CJ. Ubah OC, et al. Among authors: aihara h. Nat Commun. 2021 Dec 16;12(1):7325. doi: 10.1038/s41467-021-27611-y. Nat Commun. 2021. PMID: 34916516 Free PMC article.
Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors.
Moghadasi SA, Heilmann E, Khalil AM, Nnabuife C, Kearns FL, Ye C, Moraes SN, Costacurta F, Esler MA, Aihara H, von Laer D, Martinez-Sobrido L, Palzkill T, Amaro RE, Harris RS. Moghadasi SA, et al. Among authors: aihara h. bioRxiv [Preprint]. 2022 Dec 26:2022.08.07.503099. doi: 10.1101/2022.08.07.503099. bioRxiv. 2022. Update in: Sci Adv. 2023 Mar 29;9(13):eade8778. doi: 10.1126/sciadv.ade8778. PMID: 35982678 Free PMC article. Updated. Preprint.
Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein.
Bosnakovski D, Toso EA, Ener ET, Gearhart MD, Yin L, Lüttmann FF, Magli A, Shi K, Kim J, Aihara H, Kyba M. Bosnakovski D, et al. Among authors: aihara h. bioRxiv [Preprint]. 2023 Jan 22:2023.01.21.524976. doi: 10.1101/2023.01.21.524976. bioRxiv. 2023. Update in: iScience. 2023 Sep 02;26(10):107823. doi: 10.1016/j.isci.2023.107823. PMID: 36711898 Free PMC article. Updated. Preprint.
871 results