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Page 1
Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data.
Viney NJ, Guo S, Tai LJ, Baker BF, Aghajan M, Jung SW, Yu RZ, Booten S, Murray H, Machemer T, Burel S, Murray S, Buchele G, Tsimikas S, Schneider E, Geary RS, Benson MD, Monia BP. Viney NJ, et al. Among authors: buchele g. ESC Heart Fail. 2021 Feb;8(1):652-661. doi: 10.1002/ehf2.13154. Epub 2020 Dec 7. ESC Heart Fail. 2021. PMID: 33283485 Free PMC article. Clinical Trial.
Design and Rationale of the Global Phase 3 NEURO-TTRansform Study of Antisense Oligonucleotide AKCEA-TTR-LRx (ION-682884-CS3) in Hereditary Transthyretin-Mediated Amyloid Polyneuropathy.
Coelho T, Ando Y, Benson MD, Berk JL, Waddington-Cruz M, Dyck PJ, Gillmore JD, Khella SL, Litchy WJ, Obici L, Monteiro C, Tai LJ, Viney NJ, Buchele G, Brambatti M, Jung SW, St L O'Dea L, Tsimikas S, Schneider E, Geary RS, Monia BP, Gertz M. Coelho T, et al. Among authors: buchele g. Neurol Ther. 2021 Jun;10(1):375-389. doi: 10.1007/s40120-021-00235-6. Epub 2021 Feb 26. Neurol Ther. 2021. PMID: 33638113 Free PMC article.
Enabling patient-reported outcome measures in clinical trials, exemplified by cardiovascular trials.
Coles TM, Hernandez AF, Reeve BB, Cook K, Edwards MC, Boutin M, Bush E, Degboe A, Roessig L, Rudolph A, McNulty P, Patel N, Kay-Mugford T, Vernon M, Woloschak M, Buchele G, Spertus JA, Roe MT, Bury D, Weinfurt K. Coles TM, et al. Among authors: buchele g. Health Qual Life Outcomes. 2021 Jun 13;19(1):164. doi: 10.1186/s12955-021-01800-1. Health Qual Life Outcomes. 2021. PMID: 34120618 Free PMC article.
Correction: Health-economic evaluation of orthogeriatric co-management for patients with forearm or humerus fractures: an analysis of insurance claims data from Germany.
Henken E, Konig HH, Becker C, Buchele G, Friess T, Jaensch A, Rapp K, Rothenbacher D, Konnopka C. Henken E, et al. Among authors: buchele g. BMC Health Serv Res. 2024 Nov 1;24(1):1336. doi: 10.1186/s12913-024-11864-6. BMC Health Serv Res. 2024. PMID: 39487498 Free PMC article. No abstract available.
Association of orthogeriatric co-management with prescription frequencies of anti-osteoporotic drugs in patients with fragility fractures: An observational study with health insurance data.
Rapp K, Schöne D, Roigk P, Becker C, Jaensch A, Rothenbacher D, Konnopka C, König HH, Gosch M, Friess T, Büchele G. Rapp K, et al. Among authors: buchele g. Injury. 2024 Oct 18;55(12):111971. doi: 10.1016/j.injury.2024.111971. Online ahead of print. Injury. 2024. PMID: 39486395
Correction: Prevention at home in older persons with (pre-)frailty: analysis of participants' recruitment and characteristics of the randomized controlled PromeTheus trial.
Fleiner T, Nerz C, Denkinger M, Bauer JM, Grüneberg C, Dams J, Schäufele M, Büchele G; PromeTheus Study Group; Rapp K, Werner C. Fleiner T, et al. Among authors: buchele g. Aging Clin Exp Res. 2024 Sep 23;36(1):195. doi: 10.1007/s40520-024-02837-0. Aging Clin Exp Res. 2024. PMID: 39312093 Free PMC article. No abstract available.
Implementation of a multimodal home-based rehabilitation intervention after discharge from inpatient geriatric rehabilitation (GeRas): an early qualitative process evaluation.
Roth C, Maier L, Abel B, Roigk P, Rapp K, Schmidberger O, Bongartz M, Maier S, Wirth I, Metz B, Immel D, Finger B, Schölch S, Büchele G, Deuster O, Koenig HH, Gottschalk S, Dams J, Micol W, Bauer JM, Wensing M, Benzinger P. Roth C, et al. Among authors: buchele g. BMC Geriatr. 2024 Aug 29;24(1):720. doi: 10.1186/s12877-024-05277-7. BMC Geriatr. 2024. PMID: 39210258 Free PMC article.
Older patients with vertebral and pelvic fractures: Study protocol of a clinical cohort.
Roigk P, Leonhardt R, Lindemann U, Abel B, Büchele G, Rothenbacher D, Koschate J, Schlotmann J, Elsayed M, Zieschang T, Laurentius T, Bollheimer C, Becker C, Rapp K. Roigk P, et al. Among authors: buchele g. PLoS One. 2024 Aug 27;19(8):e0306727. doi: 10.1371/journal.pone.0306727. eCollection 2024. PLoS One. 2024. PMID: 39190760 Free PMC article.
144 results