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Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data.
Viney NJ, Guo S, Tai LJ, Baker BF, Aghajan M, Jung SW, Yu RZ, Booten S, Murray H, Machemer T, Burel S, Murray S, Buchele G, Tsimikas S, Schneider E, Geary RS, Benson MD, Monia BP. Viney NJ, et al. Among authors: murray s, murray h. ESC Heart Fail. 2021 Feb;8(1):652-661. doi: 10.1002/ehf2.13154. Epub 2020 Dec 7. ESC Heart Fail. 2021. PMID: 33283485 Free PMC article. Clinical Trial.
miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting.
Esau C, Davis S, Murray SF, Yu XX, Pandey SK, Pear M, Watts L, Booten SL, Graham M, McKay R, Subramaniam A, Propp S, Lollo BA, Freier S, Bennett CF, Bhanot S, Monia BP. Esau C, et al. Among authors: murray sf. Cell Metab. 2006 Feb;3(2):87-98. doi: 10.1016/j.cmet.2006.01.005. Cell Metab. 2006. PMID: 16459310 Free article.
Specific reduction of hepatic glucose 6-phosphate transporter-1 ameliorates diabetes while avoiding complications of glycogen storage disease.
Sloop KW, Showalter AD, Cox AL, Cao JX, Siesky AM, Zhang HY, Irizarry AR, Murray SF, Booten SL, Finger EA, McKay RA, Monia BP, Bhanot S, Michael MD. Sloop KW, et al. Among authors: murray sf. J Biol Chem. 2007 Jun 29;282(26):19113-21. doi: 10.1074/jbc.M610759200. Epub 2007 May 3. J Biol Chem. 2007. PMID: 17478431 Free article.
Inhibition of protein tyrosine phosphatase-1B with antisense oligonucleotides improves insulin sensitivity and increases adiponectin concentrations in monkeys.
Swarbrick MM, Havel PJ, Levin AA, Bremer AA, Stanhope KL, Butler M, Booten SL, Graham JL, McKay RA, Murray SF, Watts LM, Monia BP, Bhanot S. Swarbrick MM, et al. Among authors: murray sf. Endocrinology. 2009 Apr;150(4):1670-9. doi: 10.1210/en.2008-0885. Epub 2009 Jan 22. Endocrinology. 2009. PMID: 19164474 Free PMC article.
Single-stranded siRNAs activate RNAi in animals.
Lima WF, Prakash TP, Murray HM, Kinberger GA, Li W, Chappell AE, Li CS, Murray SF, Gaus H, Seth PP, Swayze EE, Crooke ST. Lima WF, et al. Among authors: murray sf, murray hm. Cell. 2012 Aug 31;150(5):883-94. doi: 10.1016/j.cell.2012.08.014. Cell. 2012. PMID: 22939618 Free article.
3,335 results