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The lectin-like domain of TNF protects from listeriolysin-induced hyperpermeability in human pulmonary microvascular endothelial cells - a crucial role for protein kinase C-alpha inhibition.
Xiong C, Yang G, Kumar S, Aggarwal S, Leustik M, Snead C, Hamacher J, Fischer B, Umapathy NS, Hossain H, Wendel A, Catravas JD, Verin AD, Fulton D, Black SM, Chakraborty T, Lucas R. Xiong C, et al. Among authors: lucas r. Vascul Pharmacol. 2010 May-Jun;52(5-6):207-13. doi: 10.1016/j.vph.2009.12.010. Epub 2010 Jan 13. Vascul Pharmacol. 2010. PMID: 20074664 Free PMC article.
Protein kinase C-α and arginase I mediate pneumolysin-induced pulmonary endothelial hyperpermeability.
Lucas R, Yang G, Gorshkov BA, Zemskov EA, Sridhar S, Umapathy NS, Jezierska-Drutel A, Alieva IB, Leustik M, Hossain H, Fischer B, Catravas JD, Verin AD, Pittet JF, Caldwell RB, Mitchell TJ, Cederbaum SD, Fulton DJ, Matthay MA, Caldwell RW, Romero MJ, Chakraborty T. Lucas R, et al. Am J Respir Cell Mol Biol. 2012 Oct;47(4):445-53. doi: 10.1165/rcmb.2011-0332OC. Epub 2012 May 10. Am J Respir Cell Mol Biol. 2012. PMID: 22582175 Free PMC article.
Lipopolysaccharide-induced lung injury involves the nitration-mediated activation of RhoA.
Rafikov R, Dimitropoulou C, Aggarwal S, Kangath A, Gross C, Pardo D, Sharma S, Jezierska-Drutel A, Patel V, Snead C, Lucas R, Verin A, Fulton D, Catravas JD, Black SM. Rafikov R, et al. Among authors: lucas r. J Biol Chem. 2014 Feb 21;289(8):4710-22. doi: 10.1074/jbc.M114.547596. Epub 2014 Jan 7. J Biol Chem. 2014. PMID: 24398689 Free PMC article.
Regulation of NADPH oxidase 5 by protein kinase C isoforms.
Chen F, Yu Y, Haigh S, Johnson J, Lucas R, Stepp DW, Fulton DJ. Chen F, et al. Among authors: lucas r. PLoS One. 2014 Feb 5;9(2):e88405. doi: 10.1371/journal.pone.0088405. eCollection 2014. PLoS One. 2014. PMID: 24505490 Free PMC article.
Arginase in the vascular endothelium: friend or foe?
Lucas R, Fulton D, Caldwell RW, Romero MJ. Lucas R, et al. Front Immunol. 2014 Nov 17;5:589. doi: 10.3389/fimmu.2014.00589. eCollection 2014. Front Immunol. 2014. PMID: 25452758 Free PMC article. No abstract available.
1,895 results