Taylor DL - Search Results

1

Human biomimetic liver microphysiology systems in drug development and precision medicine.

Gough A, Soto-Gutierrez A, Vernetti L, Ebrahimkhani MR, Stern AM, Taylor DL. Gough A, et al. Among authors: taylor dl. Nat Rev Gastroenterol Hepatol. 2021 Apr;18(4):252-268. doi: 10.1038/s41575-020-00386-1. Epub 2020 Dec 17. Nat Rev Gastroenterol Hepatol. 2021. PMID: 33335282 Free PMC article. Review.

2

Fluorescence anisotropy imaging microscopy maps calmodulin binding during cellular contraction and locomotion.

Gough AH, Taylor DL. Gough AH, et al. Among authors: taylor dl. J Cell Biol. 1993 Jun;121(5):1095-107. doi: 10.1083/jcb.121.5.1095. J Cell Biol. 1993. PMID: 8501117 Free PMC article.

3

Systems cell biology based on high-content screening.

Giuliano KA, Johnston PA, Gough A, Taylor DL. Giuliano KA, et al. Among authors: taylor dl. Methods Enzymol. 2006;414:601-19. doi: 10.1016/S0076-6879(06)14031-8. Methods Enzymol. 2006. PMID: 17110213 Review.

4

Early safety assessment using cellular systems biology yields insights into mechanisms of action.

Giuliano KA, Gough AH, Taylor DL, Vernetti LA, Johnston PA. Giuliano KA, et al. Among authors: taylor dl. J Biomol Screen. 2010 Aug;15(7):783-97. doi: 10.1177/1087057110376413. Epub 2010 Jul 16. J Biomol Screen. 2010. PMID: 20639501

5

In vitro platforms for evaluating liver toxicity.

Bale SS, Vernetti L, Senutovitch N, Jindal R, Hegde M, Gough A, McCarty WJ, Bakan A, Bhushan A, Shun TY, Golberg I, DeBiasio R, Usta BO, Taylor DL, Yarmush ML. Bale SS, et al. Among authors: taylor dl. Exp Biol Med (Maywood). 2014 Sep;239(9):1180-1191. doi: 10.1177/1535370214531872. Epub 2014 Apr 24. Exp Biol Med (Maywood). 2014. PMID: 24764241 Free PMC article. Review.

6

Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery.

Gough AH, Chen N, Shun TY, Lezon TR, Boltz RC, Reese CE, Wagner J, Vernetti LA, Grandis JR, Lee AV, Stern AM, Schurdak ME, Taylor DL. Gough AH, et al. Among authors: taylor dl. PLoS One. 2014 Jul 18;9(7):e102678. doi: 10.1371/journal.pone.0102678. eCollection 2014. PLoS One. 2014. PMID: 25036749 Free PMC article.

7

Fluorescent protein biosensors applied to microphysiological systems.

Senutovitch N, Vernetti L, Boltz R, DeBiasio R, Gough A, Taylor DL. Senutovitch N, et al. Among authors: taylor dl. Exp Biol Med (Maywood). 2015 Jun;240(6):795-808. doi: 10.1177/1535370215584934. Epub 2015 May 19. Exp Biol Med (Maywood). 2015. PMID: 25990438 Free PMC article. Review.

8

A human liver microphysiology platform for investigating physiology, drug safety, and disease models.

Vernetti LA, Senutovitch N, Boltz R, DeBiasio R, Shun TY, Gough A, Taylor DL. Vernetti LA, et al. Among authors: taylor dl. Exp Biol Med (Maywood). 2016 Jan;241(1):101-14. doi: 10.1177/1535370215592121. Epub 2015 Jul 22. Exp Biol Med (Maywood). 2016. PMID: 26202373 Free PMC article.

9

A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine.

Stern AM, Schurdak ME, Bahar I, Berg JM, Taylor DL. Stern AM, et al. Among authors: taylor dl. J Biomol Screen. 2016 Jul;21(6):521-34. doi: 10.1177/1087057116635818. Epub 2016 Mar 8. J Biomol Screen. 2016. PMID: 26962875 Free PMC article.

10

Evolution of Experimental Models of the Liver to Predict Human Drug Hepatotoxicity and Efficacy.

Vernetti LA, Vogt A, Gough A, Taylor DL. Vernetti LA, et al. Among authors: taylor dl. Clin Liver Dis. 2017 Feb;21(1):197-214. doi: 10.1016/j.cld.2016.08.013. Clin Liver Dis. 2017. PMID: 27842772 Free PMC article. Review.

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