Yang H - Search Results

1

Active-Site Controlled, Jahn-Teller Enabled Regioselectivity in Reductive S-C Bond Cleavage of S-Adenosylmethionine in Radical SAM Enzymes.

Impano S, Yang H, Jodts RJ, Pagnier A, Swimley R, McDaniel EC, Shepard EM, Broderick WE, Broderick JB, Hoffman BM. Impano S, et al. Among authors: yang h. J Am Chem Soc. 2021 Jan 13;143(1):335-348. doi: 10.1021/jacs.0c10925. Epub 2020 Dec 29. J Am Chem Soc. 2021. PMID: 33372786 Free PMC article.

2

Spectroscopic and mechanistic studies of heterodimetallic forms of metallo-β-lactamase NDM-1.

Yang H, Aitha M, Marts AR, Hetrick A, Bennett B, Crowder MW, Tierney DL. Yang H, et al. J Am Chem Soc. 2014 May 21;136(20):7273-85. doi: 10.1021/ja410376s. Epub 2014 May 12. J Am Chem Soc. 2014. PMID: 24754678 Free PMC article.

3

Paradigm Shift for Radical S-Adenosyl-l-methionine Reactions: The Organometallic Intermediate Ω Is Central to Catalysis.

Byer AS, Yang H, McDaniel EC, Kathiresan V, Impano S, Pagnier A, Watts H, Denler C, Vagstad AL, Piel J, Duschene KS, Shepard EM, Shields TP, Scott LG, Lilla EA, Yokoyama K, Broderick WE, Hoffman BM, Broderick JB. Byer AS, et al. Among authors: yang h. J Am Chem Soc. 2018 Jul 18;140(28):8634-8638. doi: 10.1021/jacs.8b04061. Epub 2018 Jul 6. J Am Chem Soc. 2018. PMID: 29954180 Free PMC article.

4

ENDOR Characterization of (N₂)Fe^II(μ-H)₂Fe^I(N₂)^-: A Spectroscopic Model for N₂ Binding by the Di-μ-hydrido Nitrogenase Janus Intermediate.

Yang H, Rittle J, Marts AR, Peters JC, Hoffman BM. Yang H, et al. Inorg Chem. 2018 Oct 1;57(19):12323-12330. doi: 10.1021/acs.inorgchem.8b02021. Epub 2018 Sep 17. Inorg Chem. 2018. PMID: 30222330 Free PMC article.

5

The Elusive 5'-Deoxyadenosyl Radical: Captured and Characterized by Electron Paramagnetic Resonance and Electron Nuclear Double Resonance Spectroscopies.

Yang H, McDaniel EC, Impano S, Byer AS, Jodts RJ, Yokoyama K, Broderick WE, Broderick JB, Hoffman BM. Yang H, et al. J Am Chem Soc. 2019 Jul 31;141(30):12139-12146. doi: 10.1021/jacs.9b05926. Epub 2019 Jul 22. J Am Chem Soc. 2019. PMID: 31274303 Free PMC article.

6

Photoinduced Electron Transfer in a Radical SAM Enzyme Generates an S-Adenosylmethionine Derived Methyl Radical.

Yang H, Impano S, Shepard EM, James CD, Broderick WE, Broderick JB, Hoffman BM. Yang H, et al. J Am Chem Soc. 2019 Oct 9;141(40):16117-16124. doi: 10.1021/jacs.9b08541. Epub 2019 Sep 26. J Am Chem Soc. 2019. PMID: 31509404 Free PMC article.

7

Radical SAM Enzyme Spore Photoproduct Lyase: Properties of the Ω Organometallic Intermediate and Identification of Stable Protein Radicals Formed during Substrate-Free Turnover.

Pagnier A, Yang H, Jodts RJ, James CD, Shepard EM, Impano S, Broderick WE, Hoffman BM, Broderick JB. Pagnier A, et al. Among authors: yang h. J Am Chem Soc. 2020 Oct 28;142(43):18652-18660. doi: 10.1021/jacs.0c08585. Epub 2020 Oct 15. J Am Chem Soc. 2020. PMID: 32966073 Free PMC article.

8

Structural and spectroscopic characterization of an Fe(VI) bis(imido) complex.

Martinez JL, Lutz SA, Yang H, Xie J, Telser J, Hoffman BM, Carta V, Pink M, Losovyj Y, Smith JM. Martinez JL, et al. Among authors: yang h. Science. 2020 Oct 16;370(6514):356-359. doi: 10.1126/science.abd3054. Science. 2020. PMID: 33060362

9

S-Adenosyl-l-ethionine is a Catalytically Competent Analog of S-Adenosyl-l-methione (SAM) in the Radical SAM Enzyme HydG.

Impano S, Yang H, Shepard EM, Swimley R, Pagnier A, Broderick WE, Hoffman BM, Broderick JB. Impano S, et al. Among authors: yang h. Angew Chem Int Ed Engl. 2021 Feb 23;60(9):4666-4672. doi: 10.1002/anie.202014337. Epub 2020 Dec 1. Angew Chem Int Ed Engl. 2021. PMID: 33935588 Free PMC article.

10

The electronic structure of FeV-cofactor in vanadium-dependent nitrogenase.

Yang ZY, Jimenez-Vicente E, Kallas H, Lukoyanov DA, Yang H, Martin Del Campo JS, Dean DR, Hoffman BM, Seefeldt LC. Yang ZY, et al. Among authors: yang h. Chem Sci. 2021 Mar 29;12(20):6913-6922. doi: 10.1039/d0sc06561g. Chem Sci. 2021. PMID: 34123320 Free PMC article.

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