Delgoffe GM - Search Results

1

Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion.

Scharping NE, Rivadeneira DB, Menk AV, Vignali PDA, Ford BR, Rittenhouse NL, Peralta R, Wang Y, Wang Y, DePeaux K, Poholek AC, Delgoffe GM. Scharping NE, et al. Among authors: delgoffe gm. Nat Immunol. 2021 Feb;22(2):205-215. doi: 10.1038/s41590-020-00834-9. Epub 2021 Jan 4. Nat Immunol. 2021. PMID: 33398183 Free PMC article.

2

Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis.

Delgoffe GM, Woo SR, Turnis ME, Gravano DM, Guy C, Overacre AE, Bettini ML, Vogel P, Finkelstein D, Bonnevier J, Workman CJ, Vignali DA. Delgoffe GM, et al. Nature. 2013 Sep 12;501(7466):252-6. doi: 10.1038/nature12428. Epub 2013 Aug 4. Nature. 2013. PMID: 23913274 Free PMC article.

3

Feeding an army: The metabolism of T cells in activation, anergy, and exhaustion.

Delgoffe GM, Powell JD. Delgoffe GM, et al. Mol Immunol. 2015 Dec;68(2 Pt C):492-6. doi: 10.1016/j.molimm.2015.07.026. Mol Immunol. 2015. PMID: 26256793 Free PMC article. Review.

4

Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8(+) T cell differentiation.

Pollizzi KN, Sun IH, Patel CH, Lo YC, Oh MH, Waickman AT, Tam AJ, Blosser RL, Wen J, Delgoffe GM, Powell JD. Pollizzi KN, et al. Among authors: delgoffe gm. Nat Immunol. 2016 Jun;17(6):704-11. doi: 10.1038/ni.3438. Epub 2016 Apr 11. Nat Immunol. 2016. PMID: 27064374 Free PMC article.

5

PP2A's restraint of mTOR is critical for T(reg) cell activity.

Delgoffe GM. Delgoffe GM. Nat Immunol. 2016 May;17(5):478-9. doi: 10.1038/ni.3442. Nat Immunol. 2016. PMID: 27092798 No abstract available.

6

Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8(+) T Cell Exhaustion.

Bengsch B, Johnson AL, Kurachi M, Odorizzi PM, Pauken KE, Attanasio J, Stelekati E, McLane LM, Paley MA, Delgoffe GM, Wherry EJ. Bengsch B, et al. Among authors: delgoffe gm. Immunity. 2016 Aug 16;45(2):358-73. doi: 10.1016/j.immuni.2016.07.008. Epub 2016 Aug 2. Immunity. 2016. PMID: 27496729 Free PMC article.

7

The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction.

Scharping NE, Menk AV, Moreci RS, Whetstone RD, Dadey RE, Watkins SC, Ferris RL, Delgoffe GM. Scharping NE, et al. Among authors: delgoffe gm. Immunity. 2016 Aug 16;45(2):374-88. doi: 10.1016/j.immuni.2016.07.009. Epub 2016 Aug 2. Immunity. 2016. PMID: 27496732 Free PMC article.

8

The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction.

Scharping NE, Menk AV, Moreci RS, Whetstone RD, Dadey RE, Watkins SC, Ferris RL, Delgoffe GM. Scharping NE, et al. Among authors: delgoffe gm. Immunity. 2016 Sep 20;45(3):701-703. doi: 10.1016/j.immuni.2016.08.009. Epub 2016 Sep 20. Immunity. 2016. PMID: 27653602 Free article. No abstract available.

9

Filling the Tank: Keeping Antitumor T Cells Metabolically Fit for the Long Haul.

Delgoffe GM. Delgoffe GM. Cancer Immunol Res. 2016 Dec;4(12):1001-1006. doi: 10.1158/2326-6066.CIR-16-0244. Cancer Immunol Res. 2016. PMID: 27908931 Free PMC article. Review.

10

Tumor Microenvironment Metabolism: A New Checkpoint for Anti-Tumor Immunity.

Scharping NE, Delgoffe GM. Scharping NE, et al. Among authors: delgoffe gm. Vaccines (Basel). 2016 Dec 6;4(4):46. doi: 10.3390/vaccines4040046. Vaccines (Basel). 2016. PMID: 27929420 Free PMC article. Review.

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