Zhang J - Search Results

1

Delivery of single-domain antibodies into neurons using a chimeric toxin-based platform is therapeutic in mouse models of botulism.

Miyashita SI, Zhang J, Zhang S, Shoemaker CB, Dong M. Miyashita SI, et al. Among authors: zhang s, zhang j. Sci Transl Med. 2021 Jan 6;13(575):eaaz4197. doi: 10.1126/scitranslmed.aaz4197. Sci Transl Med. 2021. PMID: 33408184

2

Frizzled proteins are colonic epithelial receptors for C. difficile toxin B.

Tao L, Zhang J, Meraner P, Tovaglieri A, Wu X, Gerhard R, Zhang X, Stallcup WB, Miao J, He X, Hurdle JG, Breault DT, Brass AL, Dong M. Tao L, et al. Among authors: zhang j, zhang x. Nature. 2016 Oct 20;538(7625):350-355. doi: 10.1038/nature19799. Epub 2016 Sep 28. Nature. 2016. PMID: 27680706 Free PMC article.

3

Identification and characterization of a novel botulinum neurotoxin.

Zhang S, Masuyer G, Zhang J, Shen Y, Lundin D, Henriksson L, Miyashita SI, Martínez-Carranza M, Dong M, Stenmark P. Zhang S, et al. Among authors: zhang j. Nat Commun. 2017 Aug 3;8:14130. doi: 10.1038/ncomms14130. Nat Commun. 2017. PMID: 28770820 Free PMC article.

4

Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium.

Zhang S, Lebreton F, Mansfield MJ, Miyashita SI, Zhang J, Schwartzman JA, Tao L, Masuyer G, Martínez-Carranza M, Stenmark P, Gilmore MS, Doxey AC, Dong M. Zhang S, et al. Among authors: zhang j. Cell Host Microbe. 2018 Feb 14;23(2):169-176.e6. doi: 10.1016/j.chom.2017.12.018. Epub 2018 Jan 27. Cell Host Microbe. 2018. PMID: 29396040 Free PMC article.

5

Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B.

Chen P, Tao L, Wang T, Zhang J, He A, Lam KH, Liu Z, He X, Perry K, Dong M, Jin R. Chen P, et al. Among authors: zhang j. Science. 2018 May 11;360(6389):664-669. doi: 10.1126/science.aar1999. Science. 2018. PMID: 29748286 Free PMC article.

6

Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells.

Tao L, Tian S, Zhang J, Liu Z, Robinson-McCarthy L, Miyashita SI, Breault DT, Gerhard R, Oottamasathien S, Whelan SPJ, Dong M. Tao L, et al. Among authors: zhang j. Nat Microbiol. 2019 Oct;4(10):1760-1769. doi: 10.1038/s41564-019-0464-z. Epub 2019 Jun 3. Nat Microbiol. 2019. PMID: 31160825 Free PMC article.

7

Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy.

Yin L, Masuyer G, Zhang S, Zhang J, Miyashita SI, Burgin D, Lovelock L, Coker SF, Fu TM, Stenmark P, Dong M. Yin L, et al. Among authors: zhang s, zhang j. PLoS Biol. 2020 Mar 17;18(3):e3000618. doi: 10.1371/journal.pbio.3000618. eCollection 2020 Mar. PLoS Biol. 2020. PMID: 32182233 Free PMC article.

8

Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection.

Chen P, Zeng J, Liu Z, Thaker H, Wang S, Tian S, Zhang J, Tao L, Gutierrez CB, Xing L, Gerhard R, Huang L, Dong M, Jin R. Chen P, et al. Among authors: zhang j. Nat Commun. 2021 Jun 18;12(1):3748. doi: 10.1038/s41467-021-23878-3. Nat Commun. 2021. PMID: 34145250 Free PMC article.

9

Knockin mouse models demonstrate differential contributions of synaptotagmin-1 and -2 as receptors for botulinum neurotoxins.

Thaker H, Zhang J, Miyashita SI, Cristofaro V, Park S, Hashemi Gheinani A, Sullivan MP, Adam RM, Dong M. Thaker H, et al. Among authors: zhang j. PLoS Pathog. 2021 Oct 18;17(10):e1009994. doi: 10.1371/journal.ppat.1009994. eCollection 2021 Oct. PLoS Pathog. 2021. PMID: 34662366 Free PMC article.

10

Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors.

Xiong X, Tian S, Yang P, Lebreton F, Bao H, Sheng K, Yin L, Chen P, Zhang J, Qi W, Ruan J, Wu H, Chen H, Breault DT, Wu H, Earl AM, Gilmore MS, Abraham J, Dong M. Xiong X, et al. Among authors: zhang j. Cell. 2022 Mar 31;185(7):1157-1171.e22. doi: 10.1016/j.cell.2022.02.002. Epub 2022 Mar 7. Cell. 2022. PMID: 35259335 Free PMC article.

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