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Positive epistasis between disease-causing missense mutations and silent polymorphism with effect on mRNA translation velocity.
Rauscher R, Bampi GB, Guevara-Ferrer M, Santos LA, Joshi D, Mark D, Strug LJ, Rommens JM, Ballmann M, Sorscher EJ, Oliver KE, Ignatova Z. Rauscher R, et al. Among authors: ignatova z. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2010612118. doi: 10.1073/pnas.2010612118. Proc Natl Acad Sci U S A. 2021. PMID: 33468668 Free PMC article.
Tuning innate immunity by translation.
Rauscher R, Ignatova Z. Rauscher R, et al. Among authors: ignatova z. Biochem Soc Trans. 2015 Dec;43(6):1247-52. doi: 10.1042/BST20150166. Biochem Soc Trans. 2015. PMID: 26614668 Review.
Alteration of protein function by a silent polymorphism linked to tRNA abundance.
Kirchner S, Cai Z, Rauscher R, Kastelic N, Anding M, Czech A, Kleizen B, Ostedgaard LS, Braakman I, Sheppard DN, Ignatova Z. Kirchner S, et al. Among authors: ignatova z. PLoS Biol. 2017 May 16;15(5):e2000779. doi: 10.1371/journal.pbio.2000779. eCollection 2017 May. PLoS Biol. 2017. PMID: 28510592 Free PMC article.
Assessing cell-specific effects of genetic variations using tRNA microarrays.
Polte C, Wedemeyer D, Oliver KE, Wagner J, Bijvelds MJC, Mahoney J, de Jonge HR, Sorscher EJ, Ignatova Z. Polte C, et al. Among authors: ignatova z. BMC Genomics. 2019 Jul 16;20(Suppl 8):549. doi: 10.1186/s12864-019-5864-1. BMC Genomics. 2019. PMID: 31307398 Free PMC article.
Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging.
Amirbeigiarab S, Kiani P, Velazquez Sanchez A, Krisp C, Kazantsev A, Fester L, Schlüter H, Ignatova Z. Amirbeigiarab S, et al. Among authors: ignatova z. Proc Natl Acad Sci U S A. 2019 Nov 5;116(45):22567-22572. doi: 10.1073/pnas.1912060116. Epub 2019 Oct 21. Proc Natl Acad Sci U S A. 2019. PMID: 31636180 Free PMC article.
Slowing ribosome velocity restores folding and function of mutant CFTR.
Oliver KE, Rauscher R, Mijnders M, Wang W, Wolpert MJ, Maya J, Sabusap CM, Kesterson RA, Kirk KL, Rab A, Braakman I, Hong JS, Hartman JL 4th, Ignatova Z, Sorscher EJ. Oliver KE, et al. Among authors: ignatova z. J Clin Invest. 2019 Dec 2;129(12):5236-5253. doi: 10.1172/JCI124282. J Clin Invest. 2019. PMID: 31657788 Free PMC article.
Fine-tuning the metabolic rewiring and adaptation of translational machinery during an epithelial-mesenchymal transition in breast cancer cells.
Fernández-Calero T, Davyt M, Perelmuter K, Chalar C, Bampi G, Persson H, Tosar JP, Hafstað V, Naya H, Rovira C, Bollati-Fogolín M, Ehrlich R, Flouriot G, Ignatova Z, Marín M. Fernández-Calero T, et al. Among authors: ignatova z. Cancer Metab. 2020 Jul 19;8:8. doi: 10.1186/s40170-020-00216-7. eCollection 2020. Cancer Metab. 2020. PMID: 32699630 Free PMC article.
126 results