Rauscher R - Search Results

1

Positive epistasis between disease-causing missense mutations and silent polymorphism with effect on mRNA translation velocity.

Rauscher R, Bampi GB, Guevara-Ferrer M, Santos LA, Joshi D, Mark D, Strug LJ, Rommens JM, Ballmann M, Sorscher EJ, Oliver KE, Ignatova Z. Rauscher R, et al. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2010612118. doi: 10.1073/pnas.2010612118. Proc Natl Acad Sci U S A. 2021. PMID: 33468668 Free PMC article.

2

Efficient translation initiation dictates codon usage at gene start.

Bentele K, Saffert P, Rauscher R, Ignatova Z, Blüthgen N. Bentele K, et al. Among authors: rauscher r. Mol Syst Biol. 2013 Jun 18;9:675. doi: 10.1038/msb.2013.32. Mol Syst Biol. 2013. PMID: 23774758 Free PMC article.

3

Tuning innate immunity by translation.

Rauscher R, Ignatova Z. Rauscher R, et al. Biochem Soc Trans. 2015 Dec;43(6):1247-52. doi: 10.1042/BST20150166. Biochem Soc Trans. 2015. PMID: 26614668 Review.

4

Alteration of protein function by a silent polymorphism linked to tRNA abundance.

Kirchner S, Cai Z, Rauscher R, Kastelic N, Anding M, Czech A, Kleizen B, Ostedgaard LS, Braakman I, Sheppard DN, Ignatova Z. Kirchner S, et al. Among authors: rauscher r. PLoS Biol. 2017 May 16;15(5):e2000779. doi: 10.1371/journal.pbio.2000779. eCollection 2017 May. PLoS Biol. 2017. PMID: 28510592 Free PMC article.

5

Timing during translation matters: synonymous mutations in human pathologies influence protein folding and function.

Rauscher R, Ignatova Z. Rauscher R, et al. Biochem Soc Trans. 2018 Aug 20;46(4):937-944. doi: 10.1042/BST20170422. Epub 2018 Jul 31. Biochem Soc Trans. 2018. PMID: 30065107 Review.

6

Slowing ribosome velocity restores folding and function of mutant CFTR.

Oliver KE, Rauscher R, Mijnders M, Wang W, Wolpert MJ, Maya J, Sabusap CM, Kesterson RA, Kirk KL, Rab A, Braakman I, Hong JS, Hartman JL 4th, Ignatova Z, Sorscher EJ. Oliver KE, et al. Among authors: rauscher r. J Clin Invest. 2019 Dec 2;129(12):5236-5253. doi: 10.1172/JCI124282. J Clin Invest. 2019. PMID: 31657788 Free PMC article.

7

Global assessment of the integrated stress response in CF patient-derived airway and intestinal tissues.

Bampi GB, Rauscher R, Kirchner S, Oliver KE, Bijvelds MJC, Santos LA, Wagner J, Frizzell RA, de Jonge HR, Sorscher EJ, Ignatova Z. Bampi GB, et al. Among authors: rauscher r. J Cyst Fibros. 2020 Nov;19(6):1021-1026. doi: 10.1016/j.jcf.2020.04.005. Epub 2020 May 23. J Cyst Fibros. 2020. PMID: 32451204 Free PMC article.

8

Evolving precision: rRNA expansion segment 7S modulates translation velocity and accuracy in eukaryal ribosomes.

Rauscher R, Eggers C, Dimitrova-Paternoga L, Shankar V, Rosina A, Cristodero M, Paternoga H, Wilson DN, Leidel SA, Polacek N. Rauscher R, et al. Nucleic Acids Res. 2024 Apr 24;52(7):4021-4036. doi: 10.1093/nar/gkae067. Nucleic Acids Res. 2024. PMID: 38324474 Free PMC article.

9

rRNA expansion segment 27Lb modulates the factor recruitment capacity of the yeast ribosome and shapes the proteome.

Shankar V, Rauscher R, Reuther J, Gharib WH, Koch M, Polacek N. Shankar V, et al. Among authors: rauscher r. Nucleic Acids Res. 2020 Apr 6;48(6):3244-3256. doi: 10.1093/nar/gkaa003. Nucleic Acids Res. 2020. PMID: 31960048 Free PMC article.

10

tRNA Synthetases Are Recruited to Yeast Ribosomes by rRNA Expansion Segment 7L but Do Not Require Association for Functionality.

Krauer N, Rauscher R, Polacek N. Krauer N, et al. Among authors: rauscher r. Noncoding RNA. 2021 Nov 22;7(4):73. doi: 10.3390/ncrna7040073. Noncoding RNA. 2021. PMID: 34842814 Free PMC article.

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