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New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens.
Durcik M, Nyerges Á, Skok Ž, Skledar DG, Trontelj J, Zidar N, Ilaš J, Zega A, Cruz CD, Tammela P, Welin M, Kimbung YR, Focht D, Benek O, Révész T, Draskovits G, Szili PÉ, Daruka L, Pál C, Kikelj D, Mašič LP, Tomašič T. Durcik M, et al. Among authors: focht d. Eur J Med Chem. 2021 Mar 5;213:113200. doi: 10.1016/j.ejmech.2021.113200. Epub 2021 Jan 22. Eur J Med Chem. 2021. PMID: 33524686
Rational design of balanced dual-targeting antibiotics with limited resistance.
Nyerges A, Tomašič T, Durcik M, Revesz T, Szili P, Draskovits G, Bogar F, Skok Ž, Zidar N, Ilaš J, Zega A, Kikelj D, Daruka L, Kintses B, Vasarhelyi B, Foldesi I, Kata D, Welin M, Kimbung R, Focht D, Mašič LP, Pal C. Nyerges A, et al. Among authors: focht d. PLoS Biol. 2020 Oct 5;18(10):e3000819. doi: 10.1371/journal.pbio.3000819. eCollection 2020 Oct. PLoS Biol. 2020. PMID: 33017402 Free PMC article.
Variations on a theme: crystal forms of the amino-acid transporter MhsT.
Neumann C, Focht D, Trampari S, Lyons JA, Nissen P. Neumann C, et al. Among authors: focht d. Acta Crystallogr F Struct Biol Commun. 2022 Aug 1;78(Pt 8):297-305. doi: 10.1107/S2053230X22007154. Epub 2022 Jul 26. Acta Crystallogr F Struct Biol Commun. 2022. PMID: 35924597 Free PMC article.
Prospective de novo drug design with deep interactome learning.
Atz K, Cotos L, Isert C, Håkansson M, Focht D, Hilleke M, Nippa DF, Iff M, Ledergerber J, Schiebroek CCG, Romeo V, Hiss JA, Merk D, Schneider P, Kuhn B, Grether U, Schneider G. Atz K, et al. Among authors: focht d. Nat Commun. 2024 Apr 22;15(1):3408. doi: 10.1038/s41467-024-47613-w. Nat Commun. 2024. PMID: 38649351 Free PMC article.
Efficacy of the combination of monoclonal antibodies against the SARS-CoV-2 Beta and Delta variants.
Boonkrai C, Cotrone TS, Chaisuriyong W, Tantawichien T, Thisyakorn U, Fernandez S, Hunsawong T, Reed M, Wongtangprasert T, Audomsun T, Phakham T, Attakitbancha C, Saelao P, Focht D, Kimbung R, Welin M, Malik AA, Pisitkun T, Srisawat N. Boonkrai C, et al. Among authors: focht d. PLoS One. 2023 May 4;18(5):e0284173. doi: 10.1371/journal.pone.0284173. eCollection 2023. PLoS One. 2023. PMID: 37141227 Free PMC article.
Ozone and microstructural morphological changes of tooth enamel.
Floare AD, Focht D, Hajdu AI, Niculescu Talpoş IC, Bălean OI, Muntean CV, Sebeşan D, Jumanca DE, Găluşcan A. Floare AD, et al. Among authors: focht d. Rom J Morphol Embryol. 2022 Jul-Sep;63(3):539-544. doi: 10.47162/RJME.63.3.08. Rom J Morphol Embryol. 2022. PMID: 36588492 Free PMC article.
Telehealth for Pediatric Disorders of Gut-Brain Interaction During the COVID-19 Pandemic.
Winnick JB, Chancey L, Buzenski J, Sukumar K, Focht DR 3rd, Kuhn BR, Tabani S, Zahka NE, Williams SE. Winnick JB, et al. Among authors: focht dr 3rd. J Pediatr Gastroenterol Nutr. 2023 Apr 1;76(4):447-450. doi: 10.1097/MPG.0000000000003687. Epub 2022 Dec 29. J Pediatr Gastroenterol Nutr. 2023. PMID: 36580889 Free PMC article.
Impact of Dentistry Materials on Chemical Remineralisation/Infiltration versus Salivary Remineralisation of Enamel-In Vitro Study.
Damian LR, Dumitrescu R, Alexa VT, Focht D, Schwartz C, Balean O, Jumanca D, Obistioiu D, Lalescu D, Stefaniga SA, Berbecea A, Fratila AD, Scurtu AD, Galuscan A. Damian LR, et al. Among authors: focht d. Materials (Basel). 2022 Oct 17;15(20):7258. doi: 10.3390/ma15207258. Materials (Basel). 2022. PMID: 36295323 Free PMC article.
80 results