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ADAM8 affects glioblastoma progression by regulating osteopontin-mediated angiogenesis.
Li Y, Guo S, Zhao K, Conrad C, Driescher C, Rothbart V, Schlomann U, Guerreiro H, Bopp MH, König A, Carl B, Pagenstecher A, Nimsky C, Bartsch JW. Li Y, et al. Among authors: bartsch jw. Biol Chem. 2020 Sep 11;402(2):195-206. doi: 10.1515/hsz-2020-0184. Print 2021 Jan 27. Biol Chem. 2020. PMID: 33544472 Free article.
ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein.
Moss ML, Powell G, Miller MA, Edwards L, Qi B, Sang QX, De Strooper B, Tesseur I, Lichtenthaler SF, Taverna M, Zhong JL, Dingwall C, Ferdous T, Schlomann U, Zhou P, Griffith LG, Lauffenburger DA, Petrovich R, Bartsch JW. Moss ML, et al. Among authors: bartsch jw. J Biol Chem. 2011 Nov 25;286(47):40443-51. doi: 10.1074/jbc.M111.280495. Epub 2011 Sep 28. J Biol Chem. 2011. PMID: 21956108 Free PMC article.
ADAM8 expression in invasive breast cancer promotes tumor dissemination and metastasis.
Romagnoli M, Mineva ND, Polmear M, Conrad C, Srinivasan S, Loussouarn D, Barillé-Nion S, Georgakoudi I, Dagg Á, McDermott EW, Duffy MJ, McGowan PM, Schlomann U, Parsons M, Bartsch JW, Sonenshein GE. Romagnoli M, et al. Among authors: bartsch jw. EMBO Mol Med. 2014 Feb;6(2):278-94. doi: 10.1002/emmm.201303373. Epub 2013 Dec 27. EMBO Mol Med. 2014. PMID: 24375628 Free PMC article.
ADAM8 as a drug target in pancreatic cancer.
Schlomann U, Koller G, Conrad C, Ferdous T, Golfi P, Garcia AM, Höfling S, Parsons M, Costa P, Soper R, Bossard M, Hagemann T, Roshani R, Sewald N, Ketchem RR, Moss ML, Rasmussen FH, Miller MA, Lauffenburger DA, Tuveson DA, Nimsky C, Bartsch JW. Schlomann U, et al. Among authors: bartsch jw. Nat Commun. 2015 Jan 28;6:6175. doi: 10.1038/ncomms7175. Nat Commun. 2015. PMID: 25629724 Free PMC article.
The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells.
Dong F, Eibach M, Bartsch JW, Dolga AM, Schlomann U, Conrad C, Schieber S, Schilling O, Biniossek ML, Culmsee C, Strik H, Koller G, Carl B, Nimsky C. Dong F, et al. Among authors: bartsch jw. Neuro Oncol. 2015 Nov;17(11):1474-85. doi: 10.1093/neuonc/nov042. Epub 2015 Mar 29. Neuro Oncol. 2015. PMID: 25825051 Free PMC article.
115 results