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Page 1
Implementation of a Human Renal Proximal Tubule on a Chip for Nephrotoxicity and Drug Interaction Studies.
Vormann MK, Vriend J, Lanz HL, Gijzen L, van den Heuvel A, Hutter S, Joore J, Trietsch SJ, Stuut C, Nieskens TTG, Peters JGP, Ramp D, Caj M, Russel FGM, Jacobsen B, Roth A, Lu S, Polli JW, Naidoo AA, Vulto P, Masereeuw R, Wilmer MJ, Suter-Dick L. Vormann MK, et al. Among authors: van den heuvel a. J Pharm Sci. 2021 Apr;110(4):1601-1614. doi: 10.1016/j.xphs.2021.01.028. Epub 2021 Feb 3. J Pharm Sci. 2021. PMID: 33545187 Free article.
Nephrotoxicity and Kidney Transport Assessment on 3D Perfused Proximal Tubules.
Vormann MK, Gijzen L, Hutter S, Boot L, Nicolas A, van den Heuvel A, Vriend J, Ng CP, Nieskens TTG, van Duinen V, de Wagenaar B, Masereeuw R, Suter-Dick L, Trietsch SJ, Wilmer M, Joore J, Vulto P, Lanz HL. Vormann MK, et al. Among authors: van den heuvel a, van duinen v. AAPS J. 2018 Aug 14;20(5):90. doi: 10.1208/s12248-018-0248-z. AAPS J. 2018. PMID: 30109442
96 perfusable blood vessels to study vascular permeability in vitro.
van Duinen V, van den Heuvel A, Trietsch SJ, Lanz HL, van Gils JM, van Zonneveld AJ, Vulto P, Hankemeier T. van Duinen V, et al. Among authors: van den heuvel a, van zonneveld aj, van gils jm. Sci Rep. 2017 Dec 22;7(1):18071. doi: 10.1038/s41598-017-14716-y. Sci Rep. 2017. PMID: 29273771 Free PMC article.
Glutathione PEGylated liposomes: pharmacokinetics and delivery of cargo across the blood-brain barrier in rats.
Rip J, Chen L, Hartman R, van den Heuvel A, Reijerkerk A, van Kregten J, van der Boom B, Appeldoorn C, de Boer M, Maussang D, de Lange EC, Gaillard PJ. Rip J, et al. Among authors: van kregten j, van den heuvel a, van der boom b. J Drug Target. 2014 Jun;22(5):460-7. doi: 10.3109/1061186X.2014.888070. Epub 2014 Feb 14. J Drug Target. 2014. PMID: 24524555 Free PMC article.
Glutathione conjugation dose-dependently increases brain-specific liposomal drug delivery in vitro and in vivo.
Maussang D, Rip J, van Kregten J, van den Heuvel A, van der Pol S, van der Boom B, Reijerkerk A, Chen L, de Boer M, Gaillard P, de Vries H. Maussang D, et al. Among authors: van kregten j, van den heuvel a, van der pol s, van der boom b. Drug Discov Today Technol. 2016 Jun;20:59-69. doi: 10.1016/j.ddtec.2016.09.003. Epub 2016 Oct 13. Drug Discov Today Technol. 2016. PMID: 27986226
Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration.
Vighi E, Trifunović D, Veiga-Crespo P, Rentsch A, Hoffmann D, Sahaboglu A, Strasser T, Kulkarni M, Bertolotti E, van den Heuvel A, Peters T, Reijerkerk A, Euler T, Ueffing M, Schwede F, Genieser HG, Gaillard P, Marigo V, Ekström P, Paquet-Durand F. Vighi E, et al. Among authors: van den heuvel a. Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):E2997-E3006. doi: 10.1073/pnas.1718792115. Epub 2018 Mar 12. Proc Natl Acad Sci U S A. 2018. PMID: 29531030 Free PMC article.
Influenza A virus entry into cells lacking sialylated N-glycans.
de Vries E, de Vries RP, Wienholts MJ, Floris CE, Jacobs MS, van den Heuvel A, Rottier PJ, de Haan CA. de Vries E, et al. Among authors: van den heuvel a. Proc Natl Acad Sci U S A. 2012 May 8;109(19):7457-62. doi: 10.1073/pnas.1200987109. Epub 2012 Apr 23. Proc Natl Acad Sci U S A. 2012. PMID: 22529385 Free PMC article.
164 results