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Targeting Indoleamine 2,3-Dioxygenase in Cancer Models Using the Novel Small Molecule Inhibitor NTRC 3883-0.
Grobben Y, de Man J, van Doornmalen AM, Muller M, Willemsen-Seegers N, Vu-Pham D, Mulder WR, Prinsen MBW, de Wit J, Sterrenburg JG, van Cauter F, den Ouden JE, van Altena AM, Massuger LF, Uitdehaag JCM, Buijsman RC, Zaman GJR. Grobben Y, et al. Among authors: de man j, de wit j. Front Immunol. 2021 Jan 28;11:609490. doi: 10.3389/fimmu.2020.609490. eCollection 2020. Front Immunol. 2021. PMID: 33584686 Free PMC article.
Pharmacological validation of TDO as a target for Parkinson's disease.
Perez-Pardo P, Grobben Y, Willemsen-Seegers N, Hartog M, Tutone M, Muller M, Adolfs Y, Pasterkamp RJ, Vu-Pham D, van Doornmalen AM, van Cauter F, de Wit J, Gerard Sterrenburg J, Uitdehaag JCM, de Man J, Buijsman RC, Zaman GJR, Kraneveld AD. Perez-Pardo P, et al. Among authors: de man j, de wit j. FEBS J. 2021 Jul;288(14):4311-4331. doi: 10.1111/febs.15721. Epub 2021 Feb 18. FEBS J. 2021. PMID: 33471408 Free PMC article.
Target Residence Time-Guided Optimization on TTK Kinase Results in Inhibitors with Potent Anti-Proliferative Activity.
Uitdehaag JCM, de Man J, Willemsen-Seegers N, Prinsen MBW, Libouban MAA, Sterrenburg JG, de Wit JJP, de Vetter JRF, de Roos JADM, Buijsman RC, Zaman GJR. Uitdehaag JCM, et al. Among authors: de man j, de wit jjp, de vetter jrf, de roos jadm. J Mol Biol. 2017 Jul 7;429(14):2211-2230. doi: 10.1016/j.jmb.2017.05.014. Epub 2017 May 21. J Mol Biol. 2017. PMID: 28539250
Discovery of selective and orally available spiro-3-piperidyl ATP-competitive MK2 inhibitors.
Kaptein A, Oubrie A, de Zwart E, Hoogenboom N, de Wit J, van de Kar B, van Hoek M, Vogel G, de Kimpe V, Schultz-Fademrecht C, Borsboom J, van Zeeland M, Versteegh J, Kazemier B, de Roos J, Wijnands F, Dulos J, Jaeger M, Leandro-Garcia P, Barf T. Kaptein A, et al. Among authors: de zwart e, de roos j, de wit j, de kimpe v. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3823-7. doi: 10.1016/j.bmcl.2011.04.016. Epub 2011 Apr 16. Bioorg Med Chem Lett. 2011. PMID: 21565498
A literature review and evidence-based evaluation of the Dutch national immunisation schedule yield possibilities for improvements.
Pluijmaekers AJM, Steens A, Houweling H, Rots NY, Benschop KSM, van Binnendijk RS, Bodewes R, Brouwer JGM, Buisman A, Duizer E, van Els CACM, Hament JM, den Hartog G, Kaaijk P, Kerkhof K, King AJ, van der Klis FRM, Korthals Altes H, van der Maas NAT, van Meijeren DL, Middeldorp M, Rijnbende-Geraerts SD, Sanders EAM, Veldhuijzen IK, Vlaanderen E, Voordouw ACG, Vos ERA, de Wit J, Woudenberg T, van Vliet JA, de Melker HE. Pluijmaekers AJM, et al. Among authors: de wit j. Vaccine X. 2024 Sep 26;20:100556. doi: 10.1016/j.jvacx.2024.100556. eCollection 2024 Oct. Vaccine X. 2024. PMID: 39444596 Free PMC article. Review.
Acceptability of doxycycline prophylaxis, prior antibiotic use, and knowledge of antimicrobial resistance among Australian gay and bisexual men and non-binary people.
Holt M, Bavinton BR, Calabrese SK, Broady TR, Clackett S, Cornelisse VJ, Yu S, Gordon T, Heath-Paynter D, de Wit JBF, MacGibbon J. Holt M, et al. Among authors: de wit jbf. Sex Transm Dis. 2024 Sep 24. doi: 10.1097/OLQ.0000000000002079. Online ahead of print. Sex Transm Dis. 2024. PMID: 39316034
709 results