Indurthi DC - Search Results

1

Gain-of-function GABRB3 variants identified in vigabatrin-hypersensitive epileptic encephalopathies.

Absalom NL, Liao VWY, Kothur K, Indurthi DC, Bennetts B, Troedson C, Mohammad SS, Gupta S, McGregor IS, Bowen MT, Lederer D, Mary S, De Waele L, Jansen K, Gill D, Kurian MA, McTague A, Møller RS, Ahring PK, Dale RC, Chebib M. Absalom NL, et al. Among authors: indurthi dc. Brain Commun. 2020 Oct 1;2(2):fcaa162. doi: 10.1093/braincomms/fcaa162. eCollection 2020. Brain Commun. 2020. PMID: 33585817 Free PMC article.

2

Ligand Binding at the 4-4 Agonist-Binding Site of the 42 nAChR Triggers Receptor Activation through a Pre-Activated Conformational State.

Indurthi DC, Lewis TM, Ahring PK, Balle T, Chebib M, Absalom NL. Indurthi DC, et al. PLoS One. 2016 Aug 23;11(8):e0161154. doi: 10.1371/journal.pone.0161154. eCollection 2016. PLoS One. 2016. PMID: 27552221 Free PMC article.

3

Revisiting autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) mutations in the nicotinic acetylcholine receptor reveal an increase in efficacy regardless of stochiometry.

Indurthi DC, Qudah T, Liao VW, Ahring PK, Lewis TM, Balle T, Chebib M, Absalom NL. Indurthi DC, et al. Pharmacol Res. 2019 Jan;139:215-227. doi: 10.1016/j.phrs.2018.11.031. Epub 2018 Nov 22. Pharmacol Res. 2019. PMID: 30472464

4

AE Succinimide, an Analogue of Methyllycaconitine, When Bound Generates a Nonconducting Conformation of the α4β2 Nicotinic Acetylcholine Receptor.

Qudah T, Quek GX, Indurthi D, Karim N, Halliday JI, Absalom N, McLeod MD, Chebib M. Qudah T, et al. ACS Chem Neurosci. 2020 Feb 5;11(3):344-355. doi: 10.1021/acschemneuro.9b00525. Epub 2020 Jan 14. ACS Chem Neurosci. 2020. PMID: 31898891

5

Novel Approach for the Search for Chemical Scaffolds with Dual Activity with Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptor-A Perspective for the Treatment of Neurodegenerative Disorders.

Kowal NM, Indurthi DC, Ahring PK, Chebib M, Olafsdottir ES, Balle T. Kowal NM, et al. Among authors: indurthi dc. Molecules. 2019 Jan 27;24(3):446. doi: 10.3390/molecules24030446. Molecules. 2019. PMID: 30691196 Free PMC article.

6

Presence of multiple binding sites on α9α10 nAChR receptors alludes to stoichiometric-dependent action of the α-conotoxin, Vc1.1.

Indurthi DC, Pera E, Kim HL, Chu C, McLeod MD, McIntosh JM, Absalom NL, Chebib M. Indurthi DC, et al. Biochem Pharmacol. 2014 May 1;89(1):131-40. doi: 10.1016/j.bcp.2014.02.002. Epub 2014 Feb 15. Biochem Pharmacol. 2014. PMID: 24548457 Free PMC article.

7

Engineered α4β2 nicotinic acetylcholine receptors as models for measuring agonist binding and effect at the orthosteric low-affinity α4-α4 interface.

Ahring PK, Olsen JA, Nielsen EØ, Peters D, Pedersen MH, Rohde LA, Kastrup JS, Shahsavar A, Indurthi DC, Chebib M, Gajhede M, Balle T. Ahring PK, et al. Among authors: indurthi dc. Neuropharmacology. 2015 May;92:135-45. doi: 10.1016/j.neuropharm.2014.12.035. Epub 2015 Jan 13. Neuropharmacology. 2015. PMID: 25595102

8

Pinnatoxins E, F and G target multiple nicotinic receptor subtypes.

Hellyer SD, Indurthi D, Balle T, Runder-Varga V, Selwood AI, Tyndall JD, Chebib M, Rhodes L, Kerr DS. Hellyer SD, et al. J Neurochem. 2015 Nov;135(3):479-91. doi: 10.1111/jnc.13245. Epub 2015 Aug 3. J Neurochem. 2015. PMID: 26173951 Free article.

9

Tying up Nicotine: New Selective Competitive Antagonist of the Neuronal Nicotinic Acetylcholine Receptors.

Petersen IN, Crestey F, Jensen AA, Indurthi DC, Pedersen H, Andreasen JT, Balle T, Kristensen JL. Petersen IN, et al. Among authors: indurthi dc. ACS Med Chem Lett. 2015 Mar 4;6(4):472-5. doi: 10.1021/acsmedchemlett.5b00028. eCollection 2015 Apr 9. ACS Med Chem Lett. 2015. PMID: 25941557 Free PMC article.

10

Agonist efficiency from concentration-response curves: Structural implications and applications.

Indurthi DC, Auerbach A. Indurthi DC, et al. Biophys J. 2021 May 4;120(9):1800-1813. doi: 10.1016/j.bpj.2021.02.034. Epub 2021 Mar 4. Biophys J. 2021. PMID: 33675765 Free PMC article.

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