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Page 1
An emerging role for microglia in stress-effects on memory.
Sanguino-Gómez J, Buurstede JC, Abiega O, Fitzsimons CP, Lucassen PJ, Eggen BJL, Lesuis SL, Meijer OC, Krugers HJ. Sanguino-Gómez J, et al. Among authors: abiega o. Eur J Neurosci. 2022 May;55(9-10):2491-2518. doi: 10.1111/ejn.15188. Epub 2021 May 4. Eur J Neurosci. 2022. PMID: 33724565 Free PMC article. Review.
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation.
Yshii L, Pasciuto E, Bielefeld P, Mascali L, Lemaitre P, Marino M, Dooley J, Kouser L, Verschoren S, Lagou V, Kemps H, Gervois P, de Boer A, Burton OT, Wahis J, Verhaert J, Tareen SHK, Roca CP, Singh K, Whyte CE, Kerstens A, Callaerts-Vegh Z, Poovathingal S, Prezzemolo T, Wierda K, Dashwood A, Xie J, Van Wonterghem E, Creemers E, Aloulou M, Gsell W, Abiega O, Munck S, Vandenbroucke RE, Bronckaers A, Lemmens R, De Strooper B, Van Den Bosch L, Himmelreich U, Fitzsimons CP, Holt MG, Liston A. Yshii L, et al. Among authors: abiega o. Nat Immunol. 2022 Jun;23(6):878-891. doi: 10.1038/s41590-022-01208-z. Epub 2022 May 26. Nat Immunol. 2022. PMID: 35618831 Free PMC article.
Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome.
Diaz-Aparicio I, Paris I, Sierra-Torre V, Plaza-Zabala A, Rodríguez-Iglesias N, Márquez-Ropero M, Beccari S, Huguet P, Abiega O, Alberdi E, Matute C, Bernales I, Schulz A, Otrokocsi L, Sperlagh B, Happonen KE, Lemke G, Maletic-Savatic M, Valero J, Sierra A. Diaz-Aparicio I, et al. Among authors: abiega o. J Neurosci. 2020 Feb 12;40(7):1453-1482. doi: 10.1523/JNEUROSCI.0993-19.2019. Epub 2020 Jan 2. J Neurosci. 2020. PMID: 31896673 Free PMC article.
Neuronal hyperactivity accelerates depletion of neural stem cells and impairs hippocampal neurogenesis.
Sierra A, Martín-Suárez S, Valcárcel-Martín R, Pascual-Brazo J, Aelvoet SA, Abiega O, Deudero JJ, Brewster AL, Bernales I, Anderson AE, Baekelandt V, Maletić-Savatić M, Encinas JM. Sierra A, et al. Among authors: abiega o. Cell Stem Cell. 2015 May 7;16(5):488-503. doi: 10.1016/j.stem.2015.04.003. Cell Stem Cell. 2015. PMID: 25957904 Free PMC article.
Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling.
Abiega O, Beccari S, Diaz-Aparicio I, Nadjar A, Layé S, Leyrolle Q, Gómez-Nicola D, Domercq M, Pérez-Samartín A, Sánchez-Zafra V, Paris I, Valero J, Savage JC, Hui CW, Tremblay MÈ, Deudero JJ, Brewster AL, Anderson AE, Zaldumbide L, Galbarriatu L, Marinas A, Vivanco Md, Matute C, Maletic-Savatic M, Encinas JM, Sierra A. Abiega O, et al. PLoS Biol. 2016 May 26;14(5):e1002466. doi: 10.1371/journal.pbio.1002466. eCollection 2016 May. PLoS Biol. 2016. PMID: 27228556 Free PMC article.
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