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The BAR domain protein PICK1 regulates cell recognition and morphogenesis by interacting with Neph proteins.
Höhne M, Lorscheider J, von Bardeleben A, Dufner M, Scharf MA, Gödel M, Helmstädter M, Schurek EM, Zank S, Gerke P, Kurschat C, Sivritas SH, Neumann-Haefelin E, Huber TB, Reinhardt HC, Schauss AC, Schermer B, Fischbach KF, Benzing T. Höhne M, et al. Among authors: helmstadter m. Mol Cell Biol. 2011 Aug;31(16):3241-51. doi: 10.1128/MCB.05286-11. Epub 2011 Jun 20. Mol Cell Biol. 2011. PMID: 21690291 Free PMC article.
Functional study of mammalian Neph proteins in Drosophila melanogaster.
Helmstädter M, Lüthy K, Gödel M, Simons M, Ashish, Nihalani D, Rensing SA, Fischbach KF, Huber TB. Helmstädter M, et al. PLoS One. 2012;7(7):e40300. doi: 10.1371/journal.pone.0040300. Epub 2012 Jul 6. PLoS One. 2012. PMID: 22792268 Free PMC article.
aPKCλ/ι and aPKCζ contribute to podocyte differentiation and glomerular maturation.
Hartleben B, Widmeier E, Suhm M, Worthmann K, Schell C, Helmstädter M, Wiech T, Walz G, Leitges M, Schiffer M, Huber TB. Hartleben B, et al. Among authors: helmstadter m. J Am Soc Nephrol. 2013 Feb;24(2):253-67. doi: 10.1681/ASN.2012060582. Epub 2013 Jan 18. J Am Soc Nephrol. 2013. PMID: 23334392 Free PMC article.
N-wasp is required for stabilization of podocyte foot processes.
Schell C, Baumhakl L, Salou S, Conzelmann AC, Meyer C, Helmstädter M, Wrede C, Grahammer F, Eimer S, Kerjaschki D, Walz G, Snapper S, Huber TB. Schell C, et al. Among authors: helmstadter m. J Am Soc Nephrol. 2013 Apr;24(5):713-21. doi: 10.1681/ASN.2012080844. Epub 2013 Mar 7. J Am Soc Nephrol. 2013. PMID: 23471198 Free PMC article.
Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis.
Bechtel W, Helmstädter M, Balica J, Hartleben B, Kiefer B, Hrnjic F, Schell C, Kretz O, Liu S, Geist F, Kerjaschki D, Walz G, Huber TB. Bechtel W, et al. Among authors: helmstadter m. J Am Soc Nephrol. 2013 Apr;24(5):727-43. doi: 10.1681/ASN.2012070700. Epub 2013 Mar 14. J Am Soc Nephrol. 2013. PMID: 23492732 Free PMC article.
ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3.
Hoff S, Halbritter J, Epting D, Frank V, Nguyen TM, van Reeuwijk J, Boehlke C, Schell C, Yasunaga T, Helmstädter M, Mergen M, Filhol E, Boldt K, Horn N, Ueffing M, Otto EA, Eisenberger T, Elting MW, van Wijk JA, Bockenhauer D, Sebire NJ, Rittig S, Vyberg M, Ring T, Pohl M, Pape L, Neuhaus TJ, Elshakhs NA, Koon SJ, Harris PC, Grahammer F, Huber TB, Kuehn EW, Kramer-Zucker A, Bolz HJ, Roepman R, Saunier S, Walz G, Hildebrandt F, Bergmann C, Lienkamp SS. Hoff S, et al. Among authors: helmstadter m. Nat Genet. 2013 Aug;45(8):951-6. doi: 10.1038/ng.2681. Epub 2013 Jun 23. Nat Genet. 2013. PMID: 23793029 Free PMC article.
A brief overview on IRM function across evolution.
Helmstädter M, Höhne M, Huber TB. Helmstädter M, et al. J Neurogenet. 2014 Sep-Dec;28(3-4):264-9. doi: 10.3109/01677063.2014.918976. Epub 2014 Jul 8. J Neurogenet. 2014. PMID: 24912528 Review.
V-ATPase/mTOR signaling regulates megalin-mediated apical endocytosis.
Gleixner EM, Canaud G, Hermle T, Guida MC, Kretz O, Helmstädter M, Huber TB, Eimer S, Terzi F, Simons M. Gleixner EM, et al. Among authors: helmstadter m. Cell Rep. 2014 Jul 10;8(1):10-9. doi: 10.1016/j.celrep.2014.05.035. Epub 2014 Jun 19. Cell Rep. 2014. PMID: 24953654 Free article.
60 results