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Conformationally flexible core-bearing detergents with a hydrophobic or hydrophilic pendant: Effect of pendant polarity on detergent conformation and membrane protein stability.
Sadaf A, Kim S, Bae HE, Wang H, Nygaard A, Uegaki Y, Du Y, Munk CF, Katsube S, Sung Lee H, Bae J, Choi CW, Choi HJ, Byrne B, Gellman SH, Guan L, Loland CJ, Kobilka BK, Im W, Chae PS. Sadaf A, et al. Among authors: byrne b. Acta Biomater. 2021 Jul 1;128:393-407. doi: 10.1016/j.actbio.2021.04.043. Epub 2021 Apr 29. Acta Biomater. 2021. PMID: 33933694 Free PMC article.
Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins.
Chae PS, Rasmussen SG, Rana RR, Gotfryd K, Chandra R, Goren MA, Kruse AC, Nurva S, Loland CJ, Pierre Y, Drew D, Popot JL, Picot D, Fox BG, Guan L, Gether U, Byrne B, Kobilka B, Gellman SH. Chae PS, et al. Among authors: byrne b. Nat Methods. 2010 Dec;7(12):1003-8. doi: 10.1038/nmeth.1526. Epub 2010 Oct 31. Nat Methods. 2010. PMID: 21037590 Free PMC article.
Tandem facial amphiphiles for membrane protein stabilization.
Chae PS, Gotfryd K, Pacyna J, Miercke LJ, Rasmussen SG, Robbins RA, Rana RR, Loland CJ, Kobilka B, Stroud R, Byrne B, Gether U, Gellman SH. Chae PS, et al. Among authors: byrne b. J Am Chem Soc. 2010 Dec 1;132(47):16750-2. doi: 10.1021/ja1072959. Epub 2010 Nov 4. J Am Chem Soc. 2010. PMID: 21049926 Free PMC article.
A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins.
Chae PS, Rasmussen SG, Rana RR, Gotfryd K, Kruse AC, Manglik A, Cho KH, Nurva S, Gether U, Guan L, Loland CJ, Byrne B, Kobilka BK, Gellman SH. Chae PS, et al. Among authors: byrne b. Chemistry. 2012 Jul 27;18(31):9485-90. doi: 10.1002/chem.201200069. Epub 2012 Jun 22. Chemistry. 2012. PMID: 22730191 Free PMC article. No abstract available.
Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study.
Chae PS, Rana RR, Gotfryd K, Rasmussen SG, Kruse AC, Cho KH, Capaldi S, Carlsson E, Kobilka B, Loland CJ, Gether U, Banerjee S, Byrne B, Lee JK, Gellman SH. Chae PS, et al. Among authors: byrne b. Chem Commun (Camb). 2013 Mar 21;49(23):2287-9. doi: 10.1039/c2cc36844g. Chem Commun (Camb). 2013. PMID: 23165475 Free PMC article.
Novel tripod amphiphiles for membrane protein analysis.
Chae PS, Kruse AC, Gotfryd K, Rana RR, Cho KH, Rasmussen SG, Bae HE, Chandra R, Gether U, Guan L, Kobilka BK, Loland CJ, Byrne B, Gellman SH. Chae PS, et al. Among authors: byrne b. Chemistry. 2013 Nov 11;19(46):15645-51. doi: 10.1002/chem.201301423. Epub 2013 Oct 2. Chemistry. 2013. PMID: 24123610 Free PMC article.
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