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Conformationally flexible core-bearing detergents with a hydrophobic or hydrophilic pendant: Effect of pendant polarity on detergent conformation and membrane protein stability.
Sadaf A, Kim S, Bae HE, Wang H, Nygaard A, Uegaki Y, Du Y, Munk CF, Katsube S, Sung Lee H, Bae J, Choi CW, Choi HJ, Byrne B, Gellman SH, Guan L, Loland CJ, Kobilka BK, Im W, Chae PS. Sadaf A, et al. Among authors: chae ps. Acta Biomater. 2021 Jul 1;128:393-407. doi: 10.1016/j.actbio.2021.04.043. Epub 2021 Apr 29. Acta Biomater. 2021. PMID: 33933694 Free PMC article.
Tandem facial amphiphiles for membrane protein stabilization.
Chae PS, Gotfryd K, Pacyna J, Miercke LJ, Rasmussen SG, Robbins RA, Rana RR, Loland CJ, Kobilka B, Stroud R, Byrne B, Gether U, Gellman SH. Chae PS, et al. J Am Chem Soc. 2010 Dec 1;132(47):16750-2. doi: 10.1021/ja1072959. Epub 2010 Nov 4. J Am Chem Soc. 2010. PMID: 21049926 Free PMC article.
Structure of a nanobody-stabilized active state of the β(2) adrenoceptor.
Rasmussen SG, Choi HJ, Fung JJ, Pardon E, Casarosa P, Chae PS, Devree BT, Rosenbaum DM, Thian FS, Kobilka TS, Schnapp A, Konetzki I, Sunahara RK, Gellman SH, Pautsch A, Steyaert J, Weis WI, Kobilka BK. Rasmussen SG, et al. Among authors: chae ps. Nature. 2011 Jan 13;469(7329):175-80. doi: 10.1038/nature09648. Nature. 2011. PMID: 21228869 Free PMC article.
Structure and function of an irreversible agonist-β(2) adrenoceptor complex.
Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, Choi HJ, Devree BT, Sunahara RK, Chae PS, Gellman SH, Dror RO, Shaw DE, Weis WI, Caffrey M, Gmeiner P, Kobilka BK. Rosenbaum DM, et al. Among authors: chae ps. Nature. 2011 Jan 13;469(7329):236-40. doi: 10.1038/nature09665. Nature. 2011. PMID: 21228876 Free PMC article.
Crystal structure of the β2 adrenergic receptor-Gs protein complex.
Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, Steyaert J, Skiniotis G, Weis WI, Sunahara RK, Kobilka BK. Rasmussen SG, et al. Among authors: chae ps. Nature. 2011 Jul 19;477(7366):549-55. doi: 10.1038/nature10361. Nature. 2011. PMID: 21772288 Free PMC article.
Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex.
Westfield GH, Rasmussen SG, Su M, Dutta S, DeVree BT, Chung KY, Calinski D, Velez-Ruiz G, Oleskie AN, Pardon E, Chae PS, Liu T, Li S, Woods VL Jr, Steyaert J, Kobilka BK, Sunahara RK, Skiniotis G. Westfield GH, et al. Among authors: chae ps. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16086-91. doi: 10.1073/pnas.1113645108. Epub 2011 Sep 13. Proc Natl Acad Sci U S A. 2011. PMID: 21914848 Free PMC article.
79 results