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BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated Gq activation at early endosomes.
Wright SC, Lukasheva V, Le Gouill C, Kobayashi H, Breton B, Mailhot-Larouche S, Blondel-Tepaz É, Antunes Vieira N, Costa-Neto C, Héroux M, Lambert NA, Parreiras-E-Silva LT, Bouvier M. Wright SC, et al. Among authors: parreiras e silva lt. Proc Natl Acad Sci U S A. 2021 May 18;118(20):e2025846118. doi: 10.1073/pnas.2025846118. Proc Natl Acad Sci U S A. 2021. PMID: 33990469 Free PMC article.
A Pluridimensional View of Biased Agonism.
Costa-Neto CM, Parreiras-E-Silva LT, Bouvier M. Costa-Neto CM, et al. Mol Pharmacol. 2016 Nov;90(5):587-595. doi: 10.1124/mol.116.105940. Epub 2016 Sep 16. Mol Pharmacol. 2016. PMID: 27638872 Review.
Recent updates on GPCR biased agonism.
Pupo AS, Duarte DA, Lima V, Teixeira LB, Parreiras-E-Silva LT, Costa-Neto CM. Pupo AS, et al. Pharmacol Res. 2016 Oct;112:49-57. doi: 10.1016/j.phrs.2016.01.031. Epub 2016 Feb 2. Pharmacol Res. 2016. PMID: 26836887 Review.
Functional New World monkey oxytocin forms elicit an altered signaling profile and promotes parental care in rats.
Parreiras-E-Silva LT, Vargas-Pinilla P, Duarte DA, Longo D, Espinoza Pardo GV, Dulor Finkler A, Paixão-Côrtes VR, Paré P, Rovaris DL, Oliveira EB, Caceres RA, Gonçalves GL, Bouvier M, Salzano FM, Lucion AB, Costa-Neto CM, Bortolini MC. Parreiras-E-Silva LT, et al. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9044-9049. doi: 10.1073/pnas.1711687114. Epub 2017 Aug 7. Proc Natl Acad Sci U S A. 2017. PMID: 28784762 Free PMC article.
28 results