Hoveyda HR - Search Results

1

Randomized Controlled Trial of Neurokinin 3 Receptor Antagonist Fezolinetant for Treatment of Polycystic Ovary Syndrome.

Fraser GL, Obermayer-Pietsch B, Laven J, Griesinger G, Pintiaux A, Timmerman D, Fauser BCJM, Lademacher C, Combalbert J, Hoveyda HR, Ramael S. Fraser GL, et al. Among authors: hoveyda hr. J Clin Endocrinol Metab. 2021 Aug 18;106(9):e3519-e3532. doi: 10.1210/clinem/dgab320. J Clin Endocrinol Metab. 2021. PMID: 34000049 Free PMC article. Clinical Trial.

2

The NK3 Receptor Antagonist ESN364 Suppresses Sex Hormones in Men and Women.

Fraser GL, Ramael S, Hoveyda HR, Gheyle L, Combalbert J. Fraser GL, et al. Among authors: hoveyda hr. J Clin Endocrinol Metab. 2016 Feb;101(2):417-26. doi: 10.1210/jc.2015-3621. Epub 2015 Dec 14. J Clin Endocrinol Metab. 2016. PMID: 26653113 Clinical Trial.

3

Treatment of Menopausal Vasomotor Symptoms With Fezolinetant, a Neurokinin 3 Receptor Antagonist: A Phase 2a Trial.

Depypere H, Timmerman D, Donders G, Sieprath P, Ramael S, Combalbert J, Hoveyda HR, Fraser GL. Depypere H, et al. Among authors: hoveyda hr. J Clin Endocrinol Metab. 2019 Dec 1;104(12):5893-5905. doi: 10.1210/jc.2019-00677. J Clin Endocrinol Metab. 2019. PMID: 31415087 Clinical Trial.

4

The NK3 Receptor Antagonist ESN364 Interrupts Pulsatile LH Secretion and Moderates Levels of Ovarian Hormones Throughout the Menstrual Cycle.

Fraser GL, Hoveyda HR, Clarke IJ, Ramaswamy S, Plant TM, Rose C, Millar RP. Fraser GL, et al. Among authors: hoveyda hr. Endocrinology. 2015 Nov;156(11):4214-25. doi: 10.1210/en.2015-1409. Epub 2015 Aug 25. Endocrinology. 2015. PMID: 26305889

5

Discovery and optimization of novel antagonists to the human neurokinin-3 receptor for the treatment of sex-hormone disorders (Part I).

Hoveyda HR, Fraser GL, Roy MO, Dutheuil G, Batt F, El Bousmaqui M, Korac J, Lenoir F, Lapin A, Noël S, Blanc S. Hoveyda HR, et al. J Med Chem. 2015 Apr 9;58(7):3060-82. doi: 10.1021/jm5017413. Epub 2015 Mar 18. J Med Chem. 2015. PMID: 25738882

6

Pharmacological demarcation of the growth hormone, gut motility and feeding effects of ghrelin using a novel ghrelin receptor agonist.

Fraser GL, Hoveyda HR, Tannenbaum GS. Fraser GL, et al. Among authors: hoveyda hr. Endocrinology. 2008 Dec;149(12):6280-8. doi: 10.1210/en.2008-0804. Epub 2008 Aug 21. Endocrinology. 2008. PMID: 18719021

7

Optimization of Novel Antagonists to the Neurokinin-3 Receptor for the Treatment of Sex-Hormone Disorders (Part II).

Hoveyda HR, Fraser GL, Dutheuil G, El Bousmaqui M, Korac J, Lenoir F, Lapin A, Noël S. Hoveyda HR, et al. ACS Med Chem Lett. 2015 May 19;6(7):736-40. doi: 10.1021/acsmedchemlett.5b00117. eCollection 2015 Jul 9. ACS Med Chem Lett. 2015. PMID: 26191358 Free PMC article.

8

Effect of the ghrelin receptor agonist TZP-101 on colonic transit in a rat model of postoperative ileus.

Fraser GL, Venkova K, Hoveyda HR, Thomas H, Greenwood-Van Meerveld B. Fraser GL, et al. Among authors: hoveyda hr. Eur J Pharmacol. 2009 Feb 14;604(1-3):132-7. doi: 10.1016/j.ejphar.2008.12.011. Epub 2008 Dec 14. Eur J Pharmacol. 2009. PMID: 19121631

9

Identification of free fatty acid receptor 2 agonists using virtual screening.

Fells JI, Ai X, Weinglass A, Feng W, Lei Y, Finley M, Hoveyda HR, Fraser GL, Machacek M. Fells JI, et al. Among authors: hoveyda hr. Bioorg Med Chem Lett. 2020 Nov 1;30(21):127460. doi: 10.1016/j.bmcl.2020.127460. Epub 2020 Aug 2. Bioorg Med Chem Lett. 2020. PMID: 32755680

10

Discovery of 3-aryl-5-acylpiperazinyl-pyrazoles as antagonists to the NK3 receptor.

Hoveyda HR, Roy MO, Blanc S, Noël S, Salvino JM, Ator MA, Fraser G. Hoveyda HR, et al. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1991-6. doi: 10.1016/j.bmcl.2011.02.033. Epub 2011 Feb 13. Bioorg Med Chem Lett. 2011. PMID: 21376585

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