Peperzak V - Search Results

1

Advances and Perspectives in the Treatment of B-Cell Malignancies.

Cuenca M, Peperzak V. Cuenca M, et al. Among authors: peperzak v. Cancers (Basel). 2021 May 8;13(9):2266. doi: 10.3390/cancers13092266. Cancers (Basel). 2021. PMID: 34066840 Free PMC article.

2

Multiple myeloma with 1q21 amplification is highly sensitive to MCL-1 targeting.

Slomp A, Moesbergen LM, Gong JN, Cuenca M, von dem Borne PA, Sonneveld P, Huang DCS, Minnema MC, Peperzak V. Slomp A, et al. Among authors: peperzak v. Blood Adv. 2019 Dec 23;3(24):4202-4214. doi: 10.1182/bloodadvances.2019000702. Blood Adv. 2019. PMID: 31856269 Free PMC article.

3

Direct P70S6K1 inhibition to replace dexamethasone in synergistic combination with MCL-1 inhibition in multiple myeloma.

Spaan I, Timmerman LM, Kimman T, Slomp A, Cuenca M, van Nieuwenhuijzen N, Moesbergen LM, Minnema MC, Raymakers RA, Peperzak V. Spaan I, et al. Among authors: peperzak v. Blood Adv. 2021 Jun 22;5(12):2593-2607. doi: 10.1182/bloodadvances.2020003624. Blood Adv. 2021. PMID: 34152396 Free PMC article.

4

Multiple Myeloma Relapse Is Associated with Increased NFκB Pathway Activity and Upregulation of the Pro-Survival BCL-2 Protein BFL-1.

Spaan I, van de Stolpe A, Raymakers RA, Peperzak V. Spaan I, et al. Among authors: peperzak v. Cancers (Basel). 2021 Sep 17;13(18):4668. doi: 10.3390/cancers13184668. Cancers (Basel). 2021. PMID: 34572895 Free PMC article.

5

Targeting B-cell maturation antigen increases sensitivity of multiple myeloma cells to MCL-1 inhibition.

Cuenca M, Van Nieuwenhuijzen N, Moesbergen LM, Bloem A, Minnema MC, Peperzak V. Cuenca M, et al. Among authors: peperzak v. Haematologica. 2022 Apr 1;107(4):980-983. doi: 10.3324/haematol.2021.279517. Haematologica. 2022. PMID: 34879645 Free PMC article. No abstract available.

6

Dinaciclib synergizes with BH3 mimetics targeting BCL-2 and BCL-X_L in multiple myeloma cell lines partially dependent on MCL-1 and in plasma cells from patients.

Beltrán-Visiedo M, Jiménez-Alduán N, Díez R, Cuenca M, Benedi A, Serrano-Del Valle A, Azaceta G, Palomera L, Peperzak V, Anel A, Naval J, Marzo I. Beltrán-Visiedo M, et al. Among authors: peperzak v. Mol Oncol. 2023 Dec;17(12):2507-2525. doi: 10.1002/1878-0261.13522. Epub 2023 Sep 28. Mol Oncol. 2023. PMID: 37704591 Free PMC article.

7

Identifying clinical response to daratumumab therapy in relapsed/refractory multiple myeloma using a patient-derived in vitro model.

van Nieuwenhuijzen N, Cuenca M, Abbink L, Jak M, Peperzak V, Minnema MC. van Nieuwenhuijzen N, et al. Among authors: peperzak v. EJHaem. 2023 Nov 29;5(1):141-146. doi: 10.1002/jha2.824. eCollection 2024 Feb. EJHaem. 2023. PMID: 38406516 Free PMC article.

8

MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL.

Vikström IB, Slomp A, Carrington EM, Moesbergen LM, Chang C, Kelly GL, Glaser SP, Jansen JH, Leusen JH, Strasser A, Huang DC, Lew AM, Peperzak V, Tarlinton DM. Vikström IB, et al. Among authors: peperzak v. Cell Death Dis. 2016 Aug 25;7(8):e2345. doi: 10.1038/cddis.2016.237. Cell Death Dis. 2016. PMID: 27560714 Free PMC article.

9

Wnt signaling in multiple myeloma: a central player in disease with therapeutic potential.

Spaan I, Raymakers RA, van de Stolpe A, Peperzak V. Spaan I, et al. Among authors: peperzak v. J Hematol Oncol. 2018 May 18;11(1):67. doi: 10.1186/s13045-018-0615-3. J Hematol Oncol. 2018. PMID: 29776381 Free PMC article. Review.

10

Upcoming immunotherapeutic combinations for B-cell lymphoma.

Greve P, Meyer-Wentrup FAG, Peperzak V, Boes M. Greve P, et al. Among authors: peperzak v. Immunother Adv. 2021 Feb 9;1(1):ltab001. doi: 10.1093/immadv/ltab001. eCollection 2021 Jan. Immunother Adv. 2021. PMID: 35919738 Free PMC article. Review.

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