Maniatis T - Search Results

1

ALS- and FTD-associated missense mutations in TBK1 differentially disrupt mitophagy.

Harding O, Evans CS, Ye J, Cheung J, Maniatis T, Holzbaur ELF. Harding O, et al. Among authors: maniatis t. Proc Natl Acad Sci U S A. 2021 Jun 15;118(24):e2025053118. doi: 10.1073/pnas.2025053118. Proc Natl Acad Sci U S A. 2021. PMID: 34099552 Free PMC article.

2

Cardiac glycosides are potent inhibitors of interferon-β gene expression.

Ye J, Chen S, Maniatis T. Ye J, et al. Among authors: maniatis t. Nat Chem Biol. 2011 Jan;7(1):25-33. doi: 10.1038/nchembio.476. Epub 2010 Nov 14. Nat Chem Biol. 2011. PMID: 21076398 Free PMC article.

3

Negative regulation of interferon-β gene expression during acute and persistent virus infections.

Ye J, Maniatis T. Ye J, et al. Among authors: maniatis t. PLoS One. 2011;6(6):e20681. doi: 10.1371/journal.pone.0020681. Epub 2011 Jun 3. PLoS One. 2011. PMID: 21677781 Free PMC article.

4

A prion-like trigger of antiviral signaling.

Ye J, Maniatis T. Ye J, et al. Among authors: maniatis t. Cell. 2011 Aug 5;146(3):348-50. doi: 10.1016/j.cell.2011.07.018. Cell. 2011. PMID: 21816270 Free PMC article.

5

Intricate interplay between astrocytes and motor neurons in ALS.

Phatnani HP, Guarnieri P, Friedman BA, Carrasco MA, Muratet M, O'Keeffe S, Nwakeze C, Pauli-Behn F, Newberry KM, Meadows SK, Tapia JC, Myers RM, Maniatis T. Phatnani HP, et al. Among authors: maniatis t. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E756-65. doi: 10.1073/pnas.1222361110. Epub 2013 Feb 6. Proc Natl Acad Sci U S A. 2013. PMID: 23388633 Free PMC article.

6

hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function.

Ye J, Beetz N, O'Keeffe S, Tapia JC, Macpherson L, Chen WV, Bassel-Duby R, Olson EN, Maniatis T. Ye J, et al. Among authors: maniatis t. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):E3020-9. doi: 10.1073/pnas.1508461112. Epub 2015 May 26. Proc Natl Acad Sci U S A. 2015. PMID: 26039991 Free PMC article.

7

Distinct roles for motor neuron autophagy early and late in the SOD1^G93A mouse model of ALS.

Rudnick ND, Griffey CJ, Guarnieri P, Gerbino V, Wang X, Piersaint JA, Tapia JC, Rich MM, Maniatis T. Rudnick ND, et al. Among authors: maniatis t. Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):E8294-E8303. doi: 10.1073/pnas.1704294114. Epub 2017 Sep 13. Proc Natl Acad Sci U S A. 2017. PMID: 28904095 Free PMC article.

8

Effects of ALS-associated TANK binding kinase 1 mutations on protein-protein interactions and kinase activity.

Ye J, Cheung J, Gerbino V, Ahlsén G, Zimanyi C, Hirsh D, Maniatis T. Ye J, et al. Among authors: maniatis t. Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24517-24526. doi: 10.1073/pnas.1915732116. Epub 2019 Nov 20. Proc Natl Acad Sci U S A. 2019. PMID: 31748271 Free PMC article.

9

The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice.

Gerbino V, Kaunga E, Ye J, Canzio D, O'Keeffe S, Rudnick ND, Guarnieri P, Lutz CM, Maniatis T. Gerbino V, et al. Among authors: maniatis t. Neuron. 2020 Jun 3;106(5):789-805.e5. doi: 10.1016/j.neuron.2020.03.005. Epub 2020 Mar 27. Neuron. 2020. PMID: 32220666 Free article.

10

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

Chiu IM, Phatnani H, Kuligowski M, Tapia JC, Carrasco MA, Zhang M, Maniatis T, Carroll MC. Chiu IM, et al. Among authors: maniatis t. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20960-5. doi: 10.1073/pnas.0911405106. Epub 2009 Nov 20. Proc Natl Acad Sci U S A. 2009. PMID: 19933335 Free PMC article.

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