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Double Monoubiquitination Modifies the Molecular Recognition Properties of p15PAF Promoting Binding to the Reader Module of Dnmt1.
González-Magaña A, de Opakua AI, Merino N, Monteiro H, Diercks T, Murciano-Calles J, Luque I, Bernadó P, Cordeiro TN, Biasio A, Blanco FJ. González-Magaña A, et al. Among authors: de opakua ai. ACS Chem Biol. 2019 Oct 18;14(10):2315-2326. doi: 10.1021/acschembio.9b00679. Epub 2019 Sep 18. ACS Chem Biol. 2019. PMID: 31479228 Free article.
The Gαi-GIV binding interface is a druggable protein-protein interaction.
DiGiacomo V, de Opakua AI, Papakonstantinou MP, Nguyen LT, Merino N, Blanco-Canosa JB, Blanco FJ, Garcia-Marcos M. DiGiacomo V, et al. Among authors: de opakua ai. Sci Rep. 2017 Aug 17;7(1):8575. doi: 10.1038/s41598-017-08829-7. Sci Rep. 2017. PMID: 28819150 Free PMC article.
Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure.
Corral-Rodríguez MÁ, Stuiver M, Abascal-Palacios G, Diercks T, Oyenarte I, Ereño-Orbea J, de Opakua AI, Blanco FJ, Encinar JA, Spiwok V, Terashima H, Accardi A, Müller D, Martínez-Cruz LA. Corral-Rodríguez MÁ, et al. Among authors: de opakua ai. Biochem J. 2014 Nov 15;464(1):23-34. doi: 10.1042/BJ20140409. Biochem J. 2014. PMID: 25184538 Free PMC article.
Conformational diversity of human HP1α.
Ukmar-Godec T, Yu T, de Opakua AI, Pantoja CF, Munari F, Zweckstetter M. Ukmar-Godec T, et al. Among authors: de opakua ai. Protein Sci. 2024 Jul;33(7):e5079. doi: 10.1002/pro.5079. Protein Sci. 2024. PMID: 38895997 Free PMC article.
PCNA molecular recognition of different PIP motifs: Role of Tyr211 phosphorylation.
Ruiz-Albor A, Chaves-Arquero B, Martín-Barros I, Guerra-Castellano A, Gonzalez-Magaña A, de Opakua AI, Merino N, Ferreras-Gutiérrez M, Berra E, Díaz-Moreno I, Blanco FJ. Ruiz-Albor A, et al. Among authors: de opakua ai. Int J Biol Macromol. 2024 Jul;273(Pt 2):133187. doi: 10.1016/j.ijbiomac.2024.133187. Epub 2024 Jun 14. Int J Biol Macromol. 2024. PMID: 38880460 Free article.
12 results