Othman AA - Search Results

1

Effect of Upadacitinib on the Pharmacokinetics of Rosuvastatin or Atorvastatin in Healthy Subjects.

Mohamed MF, Coppola S, Feng T, Camp HS, Kim E, Othman AA. Mohamed MF, et al. Among authors: othman aa. Clin Pharmacol Drug Dev. 2021 Nov;10(11):1335-1344. doi: 10.1002/cpdd.957. Epub 2021 Jun 9. Clin Pharmacol Drug Dev. 2021. PMID: 34109764 Free PMC article. Clinical Trial.

2

The H3 antagonist ABT-288 is tolerated at significantly higher exposures in subjects with schizophrenia than in healthy volunteers.

Othman AA, Haig G, Florian H, Locke C, Gertsik L, Dutta S. Othman AA, et al. Br J Clin Pharmacol. 2014 Jun;77(6):965-74. doi: 10.1111/bcp.12281. Br J Clin Pharmacol. 2014. PMID: 24215171 Free PMC article. Clinical Trial.

3

Population pharmacokinetics of levodopa in subjects with advanced Parkinson's disease: levodopa-carbidopa intestinal gel infusion vs. oral tablets.

Othman AA, Dutta S. Othman AA, et al. Br J Clin Pharmacol. 2014 Jul;78(1):94-105. doi: 10.1111/bcp.12324. Br J Clin Pharmacol. 2014. PMID: 24433449 Free PMC article. Clinical Trial.

4

Pharmacokinetics of daclizumab high-yield process with repeated administration of the clinical subcutaneous regimen in patients with relapsing-remitting multiple sclerosis.

Tran JQ, Othman AA, Mikulskis A, Wolstencroft P, Elkins J. Tran JQ, et al. Among authors: othman aa. Clin Pharmacol. 2016 Feb 11;8:9-13. doi: 10.2147/CPAA.S98221. eCollection 2016. Clin Pharmacol. 2016. PMID: 26929672 Free PMC article.

5

Therapeutic protein-drug interaction assessment for daclizumab high-yield process in patients with multiple sclerosis using a cocktail approach.

Tran JQ, Othman AA, Wolstencroft P, Elkins J. Tran JQ, et al. Among authors: othman aa. Br J Clin Pharmacol. 2016 Jul;82(1):160-7. doi: 10.1111/bcp.12936. Epub 2016 May 4. Br J Clin Pharmacol. 2016. PMID: 26991517 Free PMC article. Clinical Trial.

6

Pharmacokinetics, Safety and Tolerability of ABT-494, a Novel Selective JAK 1 Inhibitor, in Healthy Volunteers and Subjects with Rheumatoid Arthritis.

Mohamed MF, Camp HS, Jiang P, Padley RJ, Asatryan A, Othman AA. Mohamed MF, et al. Among authors: othman aa. Clin Pharmacokinet. 2016 Dec;55(12):1547-1558. doi: 10.1007/s40262-016-0419-y. Clin Pharmacokinet. 2016. PMID: 27272171 Clinical Trial.

7

A Phase IIb Study of ABT-494, a Selective JAK-1 Inhibitor, in Patients With Rheumatoid Arthritis and an Inadequate Response to Anti-Tumor Necrosis Factor Therapy.

Kremer JM, Emery P, Camp HS, Friedman A, Wang L, Othman AA, Khan N, Pangan AL, Jungerwirth S, Keystone EC. Kremer JM, et al. Among authors: othman aa. Arthritis Rheumatol. 2016 Dec;68(12):2867-2877. doi: 10.1002/art.39801. Arthritis Rheumatol. 2016. PMID: 27389975 Free PMC article. Clinical Trial.

8

Efficacy and Safety of ABT-494, a Selective JAK-1 Inhibitor, in a Phase IIb Study in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate.

Genovese MC, Smolen JS, Weinblatt ME, Burmester GR, Meerwein S, Camp HS, Wang L, Othman AA, Khan N, Pangan AL, Jungerwirth S. Genovese MC, et al. Among authors: othman aa. Arthritis Rheumatol. 2016 Dec;68(12):2857-2866. doi: 10.1002/art.39808. Arthritis Rheumatol. 2016. PMID: 27390150 Free PMC article. Clinical Trial.

9

Assessment of effect of CYP3A inhibition, CYP induction, OATP1B inhibition, and high-fat meal on pharmacokinetics of the JAK1 inhibitor upadacitinib.

Mohamed MF, Jungerwirth S, Asatryan A, Jiang P, Othman AA. Mohamed MF, et al. Among authors: othman aa. Br J Clin Pharmacol. 2017 Oct;83(10):2242-2248. doi: 10.1111/bcp.13329. Epub 2017 Jun 19. Br J Clin Pharmacol. 2017. PMID: 28503781 Free PMC article. Clinical Trial.

10

Pharmacokinetics of ABT-122, a TNF-α- and IL-17A-Targeted Dual-Variable Domain Immunoglobulin, in Healthy Subjects and Patients with Rheumatoid Arthritis: Results from Three Phase I Trials.

Khatri A, Goss S, Jiang P, Mansikka H, Othman AA. Khatri A, et al. Among authors: othman aa. Clin Pharmacokinet. 2018 May;57(5):613-623. doi: 10.1007/s40262-017-0580-y. Clin Pharmacokinet. 2018. PMID: 28744796 Clinical Trial.

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