A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Liu Z, Chen K, Dai J, Xu P, Sun W, Liu W, Zhao Z, Bennett SP, Li P, Ma T, Lin Y, Kawakami A, Yu J, Wang F, Wang C, Li M, Chase P, Hodder P, Spicer TP, Scampavia L, Cao C, Pan L, Dong J, Chen Y, Yu B, Guo M, Fang P, Fisher DE, Wang J.
Liu Z, et al.
Cell Res. 2023 Jan;33(1):55-70. doi: 10.1038/s41422-022-00744-5. Epub 2023 Jan 2.
Cell Res. 2023.
PMID: 36588115
Free PMC article.