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Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer.
Luu M, Riester Z, Baldrich A, Reichardt N, Yuille S, Busetti A, Klein M, Wempe A, Leister H, Raifer H, Picard F, Muhammad K, Ohl K, Romero R, Fischer F, Bauer CA, Huber M, Gress TM, Lauth M, Danhof S, Bopp T, Nerreter T, Mulder IE, Steinhoff U, Hudecek M, Visekruna A. Luu M, et al. Among authors: romero r. Nat Commun. 2021 Jul 1;12(1):4077. doi: 10.1038/s41467-021-24331-1. Nat Commun. 2021. PMID: 34210970 Free PMC article.
The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes.
Luu M, Pautz S, Kohl V, Singh R, Romero R, Lucas S, Hofmann J, Raifer H, Vachharajani N, Carrascosa LC, Lamp B, Nist A, Stiewe T, Shaul Y, Adhikary T, Zaiss MM, Lauth M, Steinhoff U, Visekruna A. Luu M, et al. Among authors: romero r. Nat Commun. 2019 Feb 15;10(1):760. doi: 10.1038/s41467-019-08711-2. Nat Commun. 2019. PMID: 30770822 Free PMC article.
Intestinal development and homeostasis require activation and apoptosis of diet-reactive T cells.
Visekruna A, Hartmann S, Sillke YR, Glauben R, Fischer F, Raifer H, Mollenkopf H, Bertrams W, Schmeck B, Klein M, Pagenstecher A, Lohoff M, Jacob R, Pabst O, Bland PW, Luu M, Romero R, Siegmund B, Rajalingam K, Steinhoff U. Visekruna A, et al. Among authors: romero r. J Clin Invest. 2019 Apr 2;129(5):1972-1983. doi: 10.1172/JCI98929. eCollection 2019 Apr 2. J Clin Invest. 2019. PMID: 30939122 Free PMC article.
Dietary cellulose induces anti-inflammatory immunity and transcriptional programs via maturation of the intestinal microbiota.
Fischer F, Romero R, Hellhund A, Linne U, Bertrams W, Pinkenburg O, Eldin HS, Binder K, Jacob R, Walker A, Stecher B, Basic M, Luu M, Mahdavi R, Heintz-Buschart A, Visekruna A, Steinhoff U. Fischer F, et al. Among authors: romero r. Gut Microbes. 2020 Nov 9;12(1):1-17. doi: 10.1080/19490976.2020.1829962. Gut Microbes. 2020. PMID: 33079623 Free PMC article.
Selected commensals educate the intestinal vascular and immune system for immunocompetence.
Romero R, Zarzycka A, Preussner M, Fischer F, Hain T, Herrmann JP, Roth K, Keber CU, Suryamohan K, Raifer H, Luu M, Leister H, Bertrams W, Klein M, Shams-Eldin H, Jacob R, Mollenkopf HJ, Rajalingam K, Visekruna A, Steinhoff U. Romero R, et al. Microbiome. 2022 Sep 28;10(1):158. doi: 10.1186/s40168-022-01353-5. Microbiome. 2022. PMID: 36171625 Free PMC article.
Clostridium sporogenes-derived metabolites protect mice against colonic inflammation.
Krause FF, Mangold KI, Ruppert AL, Leister H, Hellhund-Zingel A, Lopez Krol A, Pesek J, Watzer B, Winterberg S, Raifer H, Binder K, Kinscherf R, Walker A, Nockher WA, Taudte RV, Bertrams W, Schmeck B, Kühl AA, Siegmund B, Romero R, Luu M, Göttig S, Bekeredjian-Ding I, Steinhoff U, Schütz B, Visekruna A. Krause FF, et al. Among authors: romero r. Gut Microbes. 2024 Jan-Dec;16(1):2412669. doi: 10.1080/19490976.2024.2412669. Epub 2024 Oct 14. Gut Microbes. 2024. PMID: 39397690 Free PMC article.
2,651 results