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Defined serum-free culture of human infant small intestinal organoids with predetermined doses of Wnt3a and R-spondin1 from surgical specimens.
Matsumoto Y, Koga H, Takahashi M, Suda K, Ochi T, Seo S, Miyano G, Miyake Y, Nakajima H, Yoshida S, Mikami T, Okazaki T, Hattori N, Yamataka A, Nakamura T. Matsumoto Y, et al. Among authors: nakamura t. Pediatr Surg Int. 2021 Nov;37(11):1543-1554. doi: 10.1007/s00383-021-04957-4. Epub 2021 Jul 3. Pediatr Surg Int. 2021. PMID: 34216241
Single cell analysis of Crohn's disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties.
Suzuki K, Murano T, Shimizu H, Ito G, Nakata T, Fujii S, Ishibashi F, Kawamoto A, Anzai S, Kuno R, Kuwabara K, Takahashi J, Hama M, Nagata S, Hiraguri Y, Takenaka K, Yui S, Tsuchiya K, Nakamura T, Ohtsuka K, Watanabe M, Okamoto R. Suzuki K, et al. Among authors: nakamura t. J Gastroenterol. 2018 Sep;53(9):1035-1047. doi: 10.1007/s00535-018-1437-3. Epub 2018 Jan 27. J Gastroenterol. 2018. PMID: 29374777 Free PMC article.
Schlafen 11 Is a Novel Target for Mucosal Regeneration in Ulcerative Colitis.
Watanabe S, Nishimura R, Shirasaki T, Katsukura N, Hibiya S, Kirimura S, Negi M, Okamoto R, Matsumoto Y, Nakamura T, Watanabe M, Tsuchiya K. Watanabe S, et al. Among authors: nakamura t. J Crohns Colitis. 2021 Sep 25;15(9):1558-1572. doi: 10.1093/ecco-jcc/jjab032. J Crohns Colitis. 2021. PMID: 33596306
Transplantation of intestinal organoids into a mouse model of colitis.
Watanabe S, Kobayashi S, Ogasawara N, Okamoto R, Nakamura T, Watanabe M, Jensen KB, Yui S. Watanabe S, et al. Among authors: nakamura t. Nat Protoc. 2022 Mar;17(3):649-671. doi: 10.1038/s41596-021-00658-3. Epub 2022 Feb 2. Nat Protoc. 2022. PMID: 35110738 Review.
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