Shen J - Search Results

1

Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin.

Hou K, Shen J, Yan J, Zhai C, Zhang J, Pan JA, Zhang Y, Jiang Y, Wang Y, Lin RZ, Cong H, Gao S, Zong WX. Hou K, et al. Among authors: shen j. EBioMedicine. 2021 Jul;69:103456. doi: 10.1016/j.ebiom.2021.103456. Epub 2021 Jul 4. EBioMedicine. 2021. PMID: 34233258 Free PMC article.

2

Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism.

Bott AJ, Shen J, Tonelli C, Zhan L, Sivaram N, Jiang YP, Yu X, Bhatt V, Chiles E, Zhong H, Maimouni S, Dai W, Velasquez S, Pan JA, Muthalagu N, Morton J, Anthony TG, Feng H, Lamers WH, Murphy DJ, Guo JY, Jin J, Crawford HC, Zhang L, White E, Lin RZ, Su X, Tuveson DA, Zong WX. Bott AJ, et al. Among authors: shen j. Cell Rep. 2019 Oct 29;29(5):1287-1298.e6. doi: 10.1016/j.celrep.2019.09.056. Cell Rep. 2019. PMID: 31665640 Free PMC article.

3

The Ubiquitin E3 Ligase TRIM21 Promotes Hepatocarcinogenesis by Suppressing the p62-Keap1-Nrf2 Antioxidant Pathway.

Wang F, Zhang Y, Shen J, Yang B, Dai W, Yan J, Maimouni S, Daguplo HQ, Coppola S, Gao Y, Wang Y, Du Z, Peng K, Liu H, Zhang Q, Tang F, Wang P, Gao S, Wang Y, Ding WX, Guo G, Wang F, Zong WX. Wang F, et al. Among authors: shen j. Cell Mol Gastroenterol Hepatol. 2021;11(5):1369-1385. doi: 10.1016/j.jcmgh.2021.01.007. Epub 2021 Jan 19. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33482392 Free PMC article.

4

Glutamine synthetase limits β-catenin-mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1.

Dai W, Shen J, Yan J, Bott AJ, Maimouni S, Daguplo HQ, Wang Y, Khayati K, Guo JY, Zhang L, Wang Y, Valvezan A, Ding WX, Chen X, Su X, Gao S, Zong WX. Dai W, et al. Among authors: shen j. J Clin Invest. 2022 Dec 15;132(24):e161408. doi: 10.1172/JCI161408. J Clin Invest. 2022. PMID: 36256480 Free PMC article.

5

Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer.

Han X, Wang D, Yang L, Wang N, Shen J, Wang J, Zhang L, Chen L, Gao S, Zong WX, Wang Y. Han X, et al. Among authors: shen j. Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2319429121. doi: 10.1073/pnas.2319429121. Epub 2024 Mar 21. Proc Natl Acad Sci U S A. 2024. PMID: 38513095 Free PMC article.

6

TRIM21-mediated ubiquitination of SQSTM1/p62 abolishes its Ser403 phosphorylation and enhances palmitic acid cytotoxicity.

Yang P, Gao S, Shen J, Liu T, Lu K, Han X, Wang J, Ni HM, Ding WX, Li H, Pan JA, Peng K, Zong WX. Yang P, et al. Among authors: shen j. Autophagy. 2024 Sep 10:1-13. doi: 10.1080/15548627.2024.2394308. Online ahead of print. Autophagy. 2024. PMID: 39172027

7

Role of reactive nitrogen species generated via inducible nitric oxide synthase in vesicant-induced lung injury, inflammation and altered lung functioning.

Sunil VR, Shen J, Patel-Vayas K, Gow AJ, Laskin JD, Laskin DL. Sunil VR, et al. Among authors: shen j. Toxicol Appl Pharmacol. 2012 May 15;261(1):22-30. doi: 10.1016/j.taap.2012.03.004. Epub 2012 Mar 14. Toxicol Appl Pharmacol. 2012. PMID: 22446026 Free PMC article.

8

Classical and alternative macrophage activation in the lung following ozone-induced oxidative stress.

Sunil VR, Patel-Vayas K, Shen J, Laskin JD, Laskin DL. Sunil VR, et al. Among authors: shen j. Toxicol Appl Pharmacol. 2012 Sep 1;263(2):195-202. doi: 10.1016/j.taap.2012.06.009. Epub 2012 Jun 19. Toxicol Appl Pharmacol. 2012. PMID: 22727909 Free PMC article.

9

Orally Administered Berberine Modulates Hepatic Lipid Metabolism by Altering Microbial Bile Acid Metabolism and the Intestinal FXR Signaling Pathway.

Sun R, Yang N, Kong B, Cao B, Feng D, Yu X, Ge C, Huang J, Shen J, Wang P, Feng S, Fei F, Guo J, He J, Aa N, Chen Q, Pan Y, Schumacher JD, Yang CS, Guo GL, Aa J, Wang G. Sun R, et al. Among authors: shen j. Mol Pharmacol. 2017 Feb;91(2):110-122. doi: 10.1124/mol.116.106617. Epub 2016 Dec 8. Mol Pharmacol. 2017. PMID: 27932556 Free PMC article.

10

Organophosphate Flame-Retardants Alter Adult Mouse Homeostasis and Gene Expression in a Sex-Dependent Manner Potentially Through Interactions With ERα.

Krumm EA, Patel VJ, Tillery TS, Yasrebi A, Shen J, Guo GL, Marco SM, Buckley BT, Roepke TA. Krumm EA, et al. Among authors: shen j. Toxicol Sci. 2018 Mar 1;162(1):212-224. doi: 10.1093/toxsci/kfx238. Toxicol Sci. 2018. PMID: 29112739 Free PMC article.

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