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291,347 results

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An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation.
Yu L, Myers G, Ku CJ, Schneider E, Wang Y, Singh SA, Jearawiriyapaisarn N, White A, Moriguchi T, Khoriaty R, Yamamoto M, Rosenfeld MG, Pedron J, Bushweller JH, Lim KC, Engel JD. Yu L, et al. Among authors: wang y. Blood. 2021 Nov 4;138(18):1691-1704. doi: 10.1182/blood.2021011682. Blood. 2021. PMID: 34324630 Free PMC article.
Epigenetic activities in erythroid cell gene regulation.
Wang Y, Yu L, Engel JD, Singh SA. Wang Y, et al. Semin Hematol. 2021 Jan;58(1):4-9. doi: 10.1053/j.seminhematol.2020.11.007. Epub 2020 Dec 15. Semin Hematol. 2021. PMID: 33509442 Free PMC article.
A new murine Rpl5 (uL18) mutation provides a unique model of variably penetrant Diamond-Blackfan anemia.
Yu L, Lemay P, Ludlow A, Guyot MC, Jones M, Mohamed FF, Saroya GA, Panaretos C, Schneider E, Wang Y, Myers G, Khoriaty R, Li Q, Franceschi R, Engel JD, Kaartinen V, Rothstein TL, Justice MJ, Kibar Z, Singh SA. Yu L, et al. Among authors: wang y. Blood Adv. 2021 Oct 26;5(20):4167-4178. doi: 10.1182/bloodadvances.2021004658. Blood Adv. 2021. PMID: 34464976 Free PMC article.
Identification of novel γ-globin inducers among all potential erythroid druggable targets.
Yu L, Myers G, Schneider E, Wang Y, Mathews R, Lim KC, Siemieniak D, Tang V, Ginsburg D, Balbin-Cuesta G, Singh SA, Phuwakanjana P, Jearawiriyapaisarn N, Khoriaty R, Engel JD. Yu L, et al. Among authors: wang y. Blood Adv. 2022 Jun 14;6(11):3280-3285. doi: 10.1182/bloodadvances.2021006802. Blood Adv. 2022. PMID: 35240686 Free PMC article.
Discovery of CBPD-268 as an Exceptionally Potent and Orally Efficacious CBP/p300 PROTAC Degrader Capable of Achieving Tumor Regression.
Chen Z, Wang M, Wu D, Bai L, Xu T, Metwally H, Wang Y, McEachern D, Zhao L, Li R, Takyi-Williams J, Wang M, Wang L, Li Q, Wen B, Sun D, Wang S. Chen Z, et al. Among authors: wang l, wang y, wang m, wang s. J Med Chem. 2024 Apr 11;67(7):5275-5304. doi: 10.1021/acs.jmedchem.3c02124. Epub 2024 Mar 13. J Med Chem. 2024. PMID: 38477974
Discovery of ERD-3111 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader with Strong Antitumor Activity.
Chen Z, Hu B, Rej RK, Wu D, Acharyya RK, Wang M, Xu T, Lu J, Metwally H, Wang Y, McEachern D, Bai L, Gersch CL, Wang M, Zhang W, Li Q, Wen B, Sun D, Rae JM, Wang S. Chen Z, et al. Among authors: wang y, wang m, wang s. J Med Chem. 2023 Sep 14;66(17):12559-12585. doi: 10.1021/acs.jmedchem.3c01186. Epub 2023 Aug 30. J Med Chem. 2023. PMID: 37647546
291,347 results
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