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Page 1
The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway.
Tauzin S, Chaigne-Delalande B, Selva E, Khadra N, Daburon S, Contin-Bordes C, Blanco P, Le Seyec J, Ducret T, Counillon L, Moreau JF, Hofman P, Vacher P, Legembre P. Tauzin S, et al. Among authors: vacher p. PLoS Biol. 2011 Jun;9(6):e1001090. doi: 10.1371/journal.pbio.1001090. Epub 2011 Jun 21. PLoS Biol. 2011. PMID: 21713032 Free PMC article.
CD95L cell surface cleavage triggers a prometastatic signaling pathway in triple-negative breast cancer.
Malleter M, Tauzin S, Bessede A, Castellano R, Goubard A, Godey F, Levêque J, Jézéquel P, Campion L, Campone M, Ducret T, MacGrogan G, Debure L, Collette Y, Vacher P, Legembre P. Malleter M, et al. Among authors: vacher p. Cancer Res. 2013 Nov 15;73(22):6711-21. doi: 10.1158/0008-5472.CAN-13-1794. Epub 2013 Sep 26. Cancer Res. 2013. PMID: 24072745
CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice.
Poissonnier A, Sanséau D, Le Gallo M, Malleter M, Levoin N, Viel R, Morere L, Penna A, Blanco P, Dupuy A, Poizeau F, Fautrel A, Seneschal J, Jouan F, Ritz J, Forcade E, Rioux N, Contin-Bordes C, Ducret T, Vacher AM, Barrow PA, Flynn RJ, Vacher P, Legembre P. Poissonnier A, et al. Among authors: vacher p, vacher am. Immunity. 2016 Jul 19;45(1):209-23. doi: 10.1016/j.immuni.2016.06.028. Immunity. 2016. PMID: 27438772 Free PMC article.
Disrupting the CD95-PLCγ1 interaction prevents Th17-driven inflammation.
Poissonnier A, Guégan JP, Nguyen HT, Best D, Levoin N, Kozlov G, Gehring K, Pineau R, Jouan F, Morere L, Martin S, Thomas M, Lazaro E, Douchet I, Ducret T, van de Weghe P, Blanco P, Jean M, Vacher P, Legembre P. Poissonnier A, et al. Among authors: vacher p. Nat Chem Biol. 2018 Dec;14(12):1079-1089. doi: 10.1038/s41589-018-0162-9. Epub 2018 Nov 14. Nat Chem Biol. 2018. PMID: 30429604
CD95/Fas and metastatic disease: What does not kill you makes you stronger.
Guégan JP, Ginestier C, Charafe-Jauffret E, Ducret T, Quignard JF, Vacher P, Legembre P. Guégan JP, et al. Among authors: vacher p. Semin Cancer Biol. 2020 Feb;60:121-131. doi: 10.1016/j.semcancer.2019.06.004. Epub 2019 Jun 6. Semin Cancer Biol. 2020. PMID: 31176682 Free article. Review.
Selectins impair regulatory T cell function and contribute to systemic lupus erythematosus pathogenesis.
Scherlinger M, Guillotin V, Douchet I, Vacher P, Boizard-Moracchini A, Guegan JP, Garreau A, Merillon N, Vermorel A, Ribeiro E, Machelart I, Lazaro E, Couzi L, Duffau P, Barnetche T, Pellegrin JL, Viallard JF, Saleh M, Schaeverbeke T, Legembre P, Truchetet ME, Dumortier H, Contin-Bordes C, Sisirak V, Richez C, Blanco P. Scherlinger M, et al. Among authors: vacher p. Sci Transl Med. 2021 Jun 30;13(600):eabi4994. doi: 10.1126/scitranslmed.abi4994. Sci Transl Med. 2021. PMID: 34193612
130 results